ChemicalBook >> CAS DataBase List >>Cyclo(D-Phe-Pro-Phe-D-Phe-Asn-Gln-Tyr-Val-Orn-Leu-)
Cyclo(D-Phe-Pro-Phe-D-Phe-Asn-Gln-Tyr-Val-Orn-Leu-)
- CAS No.
- 1481-70-5
- Chemical Name:
- Cyclo(D-Phe-Pro-Phe-D-Phe-Asn-Gln-Tyr-Val-Orn-Leu-)
- Synonyms
- Tyrocidine A;Cyclo(D-Phe-Pro-Phe-D-Phe-Asn-Gln-Tyr-Val-Orn-Leu-);Cyclo[L-Asn-L-Gln-L-Tyr-L-Val-L-Orn-L-Leu-D-Phe-L-Pro-L-Phe-D-Phe-];Cyclo(L-asparaginyl-L-glutaminyl-L-tyrosyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-phenylalanyl-D-phenylalanyl)
- CBNumber:
- CB92213267
- Molecular Formula:
- C66H87N13O13
- Molecular Weight:
- 1270.5
- MDL Number:
- MOL File:
- 1481-70-5.mol
- MSDS File:
- SDS
Last updated:2023-05-04 17:34:33
| Melting point | 240-242 °C |
|---|---|
| Boiling point | 1630.6±65.0 °C(Predicted) |
| Density | 1.33±0.1 g/cm3(Predicted) |
| pka | 9.89±0.15(Predicted) |
| FDA UNII | V134656H89 |
Cyclo(D-Phe-Pro-Phe-D-Phe-Asn-Gln-Tyr-Val-Orn-Leu-) Chemical Properties,Uses,Production
Definition
ChEBI: Tyrocidine A is a homodetic cyclic decapeptide consisting of D-Phe, L-Pro, L-Phe, D-Phe, L-Asn, L-Gln, L-Tyr, L-Val, L-Orn, and L-Leu residues coupled in sequence and cyclised head-to-tail. It has a role as an antibacterial agent and a bacterial metabolite. It is a homodetic cyclic peptide, a peptide antibiotic and a macrocycle.
Purification Methods
Crystallise tyrocidine A as the hydrochloride from MeOH or EtOH/HCl. [Paladin & Craig J Am Chem Soc 76 688 1954, King & Craig J Am Chem Soc 77 6624 1955, Okamoto et al. Bull Chem Soc Jpn 50 231 1977, Beilstein 26 III/IV 4280.]
Cyclo(D-Phe-Pro-Phe-D-Phe-Asn-Gln-Tyr-Val-Orn-Leu-) Preparation Products And Raw materials
Raw materials
Preparation Products
Cyclo(D-Phe-Pro-Phe-D-Phe-Asn-Gln-Tyr-Val-Orn-Leu-) Suppliers
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Cyclo(D-Phe-Pro-Phe-D-Phe-Asn-Gln-Tyr-Val-Orn-Leu-)
Cyclo[L-Asn-L-Gln-L-Tyr-L-Val-L-Orn-L-Leu-D-Phe-L-Pro-L-Phe-D-Phe-]
Tyrocidine A
Cyclo(L-asparaginyl-L-glutaminyl-L-tyrosyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-phenylalanyl-D-phenylalanyl)
1481-70-5