ChemicalBook >> CAS DataBase List >>GDC-0810(ARN-810)
GDC-0810(ARN-810)
- CAS No.
- 1365888-06-7
- Chemical Name:
- GDC-0810(ARN-810)
- Synonyms
- RG6046;RG 6046;CS-2080;ARN-810;RG-6046;GDC-0810;Brilanestrant);GDC-0810(ARN-810);ARN-810;BRILANESTRANT;GDC-0810 (Brilanestrant)
- CBNumber:
- CB93040499
- Molecular Formula:
- C26H20ClFN2O2
- Molecular Weight:
- 446.9
- MDL Number:
- MFCD28902190
- MOL File:
- 1365888-06-7.mol
- MSDS File:
- SDS
Last updated:2023-04-23 13:52:06
| Boiling point | 622.8±55.0 °C(Predicted) |
|---|---|
| Density | 1.342±0.06 g/cm3(Predicted) |
| solubility |
DMSO:89.0(Max Conc. mg/mL);199.15(Max Conc. mM) Ethanol:89.0(Max Conc. mg/mL);199.15(Max Conc. mM) |
| form | A solid |
| pka | 13.94±0.40(Predicted) |
| FDA UNII | 9MM2R1A06R |
GDC-0810(ARN-810) price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29595 | ARN810 | 1365888-06-7 | 5mg | $120 | 2024-03-01 | Buy |
| Cayman Chemical | 29595 | ARN810 | 1365888-06-7 | 25mg | $510 | 2024-03-01 | Buy |
| Cayman Chemical | 29595 | ARN810 | 1365888-06-7 | 1mg | $36 | 2024-03-01 | Buy |
| Cayman Chemical | 29595 | ARN810 | 1365888-06-7 | 10mg | $223 | 2024-03-01 | Buy |
| TRC | B677393 | Brilanestrant | 1365888-06-7 | 10mg | $210 | 2021-12-16 | Buy |
GDC-0810(ARN-810) Chemical Properties,Uses,Production
Uses
Brilanestrant is an orally bioavailable Selective Estrogen Receptor Degrader (SERD) that demonstrates robust activity in tamoxifen-resistant breast cancer xenografts. GDC-0810 functions by binding to the estrogen receptor, inducing a conformational change resulting in the degradation of the receptor. GDC-0810 or ARN-810 demonstrates robust activity in models of tamoxifen-sensitive and tamoxifen-resistant breast cancer, and is currently in clinical trials in women with locally advanced or metastatic estrogen receptor-positive breast cancer.
GDC-0810(ARN-810) Preparation Products And Raw materials
Raw materials
Preparation Products
GDC-0810(ARN-810) Suppliers
Global( 57)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2923 | 55 | |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 6010 | 61 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 17702719238 | sales@sun-shinechem.com | China | 918 | 64 |
1365888-06-7(GDC-0810(ARN-810))Related Search:
(E)-3-(4-((E)-2-(2-CHLORO-4-FLUOROPHENYL)-1-(1H-INDAZOL-5-YL)BUT-1-EN-1-YL)PHENYL)ACRYLIC ACID
GDC-0810(ARN-810)
GDC-0810
(E)-3-[4-[(E)-2-(2-Chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-en-1-yl]phenyl]-2-propenoic acid
GDC-0810 (Brilanestrant)
ARN-810
ARN-810;BRILANESTRANT
CS-2080
Brilanestrant)
GDC0810; GDC 0810; GDC-0810; ARN810; ARN 810; ARN-810; RG6046; RG-6046; RG 6046; BRILANESTRANT
RG 6046
RG6046
RG-6046
Brilanestrant (GDC-0810, ARN-810)
2-Propenoic acid, 3-[4-[(1E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)-1-buten-1-yl]phenyl]-, (2E)-
ARN810,inhibit,Estrogen Receptor/ERR,ARN 810,Brilanestrant,Inhibitor
Brilanestrant (GDC-0810)
1365888-06-7
C26H20ClFN2O2