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1,3-Difluorobenzene

CAS No.
372-18-9
Chemical Name:
1,3-Difluorobenzene
Synonyms
M-DIFLUOROBENZENE;1,3-DifL;DIFLOUROBENZENE;m-difluoro-benzen;m-Difluro Benzene;1,3-Difluorbenzol;3-DifluoroBenzene;1,3-DIFLUOROBENZEN;1?-Difluorobenzene;Benzene,m-difluoro-
CBNumber:
CB9853566
Molecular Formula:
C6H4F2
Molecular Weight:
114.09
MDL Number:
MFCD00000327
MOL File:
372-18-9.mol
MSDS File:
SDS
Last updated:2023-12-25 17:47:29

1,3-Difluorobenzene Properties

Melting point -59 °C
Boiling point 83 °C
Density 1.163 g/mL at 25 °C(lit.)
vapor pressure 11.034-19.924kPa at 20-38.2℃
refractive index n20/D 1.438(lit.)
Flash point 36 °F
storage temp. Flammables area
solubility 1.1g/l
form Liquid
Specific Gravity 1.163
color Clear colorless to yellow
Water Solubility insoluble
BRN 1904537
Dielectric constant 5.2400000000000002
LogP 2.21-2.52 at 25℃ and pH6.5
CAS DataBase Reference 372-18-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII VO3C26WOC2
NIST Chemistry Reference Benzene, 1,3-difluoro-(372-18-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS02
Signal word  Danger
Hazard statements  H225
Precautionary statements  P210
Hazard Codes  F,Xn
Risk Statements  11-20-2017/11/20
Safety Statements  7-16-29-33-7/9
RIDADR  UN 1993 3/PG 2
WGK Germany  1
RTECS  CZ5652000
Hazard Note  Highly Flammable
HazardClass  3
PackingGroup  II
HS Code  29036990
NFPA 704
3
2 0

1,3-Difluorobenzene price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich D102008 1,3-Difluorobenzene ≥99% 372-18-9 10g $78.6 2024-03-01 Buy
Sigma-Aldrich D102008 1,3-Difluorobenzene ≥99% 372-18-9 100g $144 2024-03-01 Buy
TCI Chemical D1626 1,3-Difluorobenzene >98.0%(GC) 372-18-9 25g $66 2024-03-01 Buy
TCI Chemical D1626 1,3-Difluorobenzene >98.0%(GC) 372-18-9 500g $457 2024-03-01 Buy
Alfa Aesar A14387 1,3-Difluorobenzene, 99% 372-18-9 10g $54.65 2024-03-01 Buy
Product number Packaging Price Buy
D102008 10g $78.6 Buy
D102008 100g $144 Buy
D1626 25g $66 Buy
D1626 500g $457 Buy
A14387 10g $54.65 Buy

1,3-Difluorobenzene Chemical Properties,Uses,Production

Synthesis

Higher yields were observed when CsF and HF were reacted with 1,3-dichlorobenzene, which gave I ,3-difluorobenzene.
synthesis of 1,3-Difluorobenzene

Chemical Properties

1,3-Difluorobenzene (C6H4F2, CAS registry No. 372-18-9) is also named as m-difluorobenzene, which is a clear colorless to yellowish liquid. Its melting point is -59 °C, boiling point is 83 °C and flash point is 2 oC. It is insoluble in water and stable under normal temperatures and pressures. It is toxic and flammable. It will produce toxic fluoride gas by heat.

Uses

1,3-Difluorobenzene has been extensively used in the synthesis of pharmaceutical and pesticide intermediate. For example, it can be used for the synthesis of fluorinated medicine such as Fluconazole, etc. and pesticide (Flucycloxuron, Diflubenzuro, etc.). It can also be used to synthesize liquid crystal materials.

Chemical Properties

CLEAR COLORLESS TO YELLOWISH LIQUID

Uses

It is used in the laser induced fluorencence matrix study of 1,3-difluorobenzene radical cation. It is also used synthesis of 1,2,3-triazole containing fluconazole analogues.

Definition

ChEBI: A difluorobenzene carrying fluoro groups at positions 1 and 3.

Global( 488)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 16805 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15932 58
Hi-Tech Chemistry Corp
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Henan Tianfu Chemical Co.,Ltd.
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Shanghai Time Chemicals CO., Ltd.
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ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32686 60
Speranza Chemical Co., Ltd.
+86-86-075521030354 +8618688942810 sophieliu@speranzachem.com China 723 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
NINGBO INNO PHARMCHEM CO., LTD.
13867897135 sales@nbinno.com CHINA 925 58

Related articles

  • What is 1,3-Difluorobenzene?
  • 1,3-Difluorobenzene (C6H4F2, CAS registry No. 372-18-9) is also named as m-difluorobenzene, which is a clear colorless to yell....
  • Feb 14,2020

View Lastest Price from 1,3-Difluorobenzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1,3-Difluorobenzene pictures 2023-12-26 1,3-Difluorobenzene
372-18-9
US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
 1,3-Difluorobenzene pictures 2023-03-06 1,3-Difluorobenzene
372-18-9
US $10.60 / KG 1KG 98% 5000kg Hebei Guanlang Biotechnology Co,.LTD
1,3-Difluorobenzene pictures 2023-02-18 1,3-Difluorobenzene
372-18-9
US $10.00 / KG 1KG 99% 10 mt Hebei Guanlang Biotechnology Co., Ltd.
1,3-difluroethylene Benzene, m-difluoro- benzene,1,3-difluoro- Benzene,m-difluoro- Between two fluorine benzene Difluoro-1,3-benzene m-difluoro-benzen meta-Difluorobenzene 1?-Difluorobenzene m-Difluro Benzene 1,3-DIFLUOROBENZEN 1,3-DIFLUOROBENZENE 1,3-DIFLUOROBENZENE, 99+% 1,3-DifluorobenzeneExtraPure DIFLOUROBENZENE 1,3-Difluorbenzol 3-DifluoroBenzene 1,3-DIFLUOROBENZENEFLOCONAZOLE 1,3 DIFLOUROBENZENE extrapure 1,3-difluoro (between the two fluorophenyl) Between difluorobenzene 1,3-Difluorobenzene, 99+% 10ML 1,3-DifL 1,3-Difluorobenzene > 1,3-Difluorobenzene ISO 9001:2015 REACH 1,3-Difluorobenzene (MDFB) extrapure, 99% M-DIFLUOROBENZENE Voriconazole Impurity 39 372-18-9 C6H4F2CFCHCFCHCHCH 372189 Building Blocks Aryl C6 Organic Building Blocks Halogenated Hydrocarbons Aryl Fluorinated Building Blocks Building Blocks Chemical Synthesis Fluorinated Building Blocks Halogenated Hydrocarbons Organic Building Blocks Organic Fluorinated Building Blocks Other Fluorinated Organic Building Blocks alkyl Fluorine Aromatic Hydrocarbons (substituted) & Derivatives Fluorobenzene Fluorine Compounds Aryl C6 Halogenated Hydrocarbons bc0001 K00001