Silane, trimethyl(2-methylene-3-buten-1-yl)- 化学特性,用途語,生産方法
物理的性質
bp 69–70 °C/80 mmHg.
使用
2-Trimethylsilylmethyl-1,3-butadiene is an isoprenylation reagent; Diels–Alder diene; reactant in Formation of π-Allylic Complex Followed by Acyldemetalation.
製造方法
2-Trimethylsilylmethyl-1,3-butadiene is prepared most conveniently by the
coupling reaction of the Grignard reagent prepared from
(chloromethyl)trimethylsilane with 2-chloro-1,3-butadiene
(chloroprene) in the presence of a catalytic amount of Ni[Ph2P-
(CH2)3PPh2]Cl2 (91% yield) (eq 1). Alternatively, it can be
prepared by the reaction of the same Grignard reagent with allenylmethyl
phosphate in 57¨C73% yield (eq 2). Direct metalation
of isoprene followed by the reaction with chlorotrimethylsilane
gives 2-trimethylsilylmethyl-1,3-butadiene in low
yield. Thermal isomerization of 1-trimethylsilylmethylcyclobutene
to 2-trimethylsilylmethyl-1,3-butadiene has also
been reported.
Silane, trimethyl(2-methylene-3-buten-1-yl)- 上流と下流の製品情報
原材料
準備製品