4-(2-ヒドロキシ-2-プロピル)-2-プロピル-1H-イミダゾール-5-カルボン酸エチル
4-(2-ヒドロキシ-2-プロピル)-2-プロピル-1H-イミダゾール-5-カルボン酸エチル 物理性質
- 融点 :
- 98-100°C
- 沸点 :
- 456.2±35.0 °C(Predicted)
- 比重(密度) :
- 1.131±0.06 g/cm3(Predicted)
- 貯蔵温度 :
- Sealed in dry,2-8°C
- 溶解性:
- クロロホルム、酢酸エチル、メタノール
- 外見 :
- 個体
- 酸解離定数(Pka):
- 11.61±0.10(Predicted)
- 色:
- ペールイエロー
- InChI:
- InChI=1S/C12H20N2O3/c1-5-7-8-13-9(11(15)17-6-2)10(14-8)12(3,4)16/h16H,5-7H2,1-4H3,(H,13,14)
- InChIKey:
- KZBJJAFGNMRRHN-UHFFFAOYSA-N
- SMILES:
- C1(CCC)NC(C(OCC)=O)=C(C(O)(C)C)N=1
- CAS データベース:
- 144689-93-0(CAS DataBase Reference)
4-(2-ヒドロキシ-2-プロピル)-2-プロピル-1H-イミダゾール-5-カルボン酸エチル 価格
もっと(19)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQV-5782 |
5-(1-Hydroxy-1-methyl-ethyl)-2-propyl-1h-imidazole-4-carboxylic acid ethyl ester |
144689-93-0 |
5g |
￥10000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQV-5782 |
5-(1-Hydroxy-1-methyl-ethyl)-2-propyl-1h-imidazole-4-carboxylic acid ethyl ester |
144689-93-0 |
25g |
￥15000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQV-5782 |
5-(1-Hydroxy-1-methyl-ethyl)-2-propyl-1h-imidazole-4-carboxylic acid ethyl ester |
144689-93-0 |
100g |
￥40000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBOR-6657 |
Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate |
144689-93-0 |
5g |
￥10000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQV-5782 |
5-(1-Hydroxy-1-methyl-ethyl)-2-propyl-1h-imidazole-4-carboxylic acid ethyl ester |
144689-93-0 |
1g |
￥10000 |
2023-06-01 |
購入 |
4-(2-ヒドロキシ-2-プロピル)-2-プロピル-1H-イミダゾール-5-カルボン酸エチル 化学特性,用途語,生産方法
外観
うすい黄赤色～黄色～緑色粉末～結晶
化学的特性
Pale Yellow Solid
主な応用
Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate is a synthetic drug with pharmacological properties that are similar to those of the natural product medoxomil. It has been shown to be a potent blocker of the GABA receptor and is used for the treatment of epilepsy.It has been shown to be an inhibitor of rat liver microsomes and also has a high affinity for the enzyme cilexetil, which is responsible for the conversion of cilexetil into its active form.
定義
Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate is a crucial intermediate for the synthesis of olmesartan medoxomil, which can be produced via the reaction of diethyl 2-propyl-imidazole-4,5-dicarboxylate, the raw material, with methylmagnesium bromide, followed by the acidification with saturated ammonium chloride solution.
危険性
Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate is sensitive to the skin and may cause allergic skin reactions. It is irritating to the skin and eyes and may also cause respiratory irritation. It is poisonous to aquatic organisms.
4-(2-ヒドロキシ-2-プロピル)-2-プロピル-1H-イミダゾール-5-カルボン酸エチル 上流と下流の製品情報
原材料
準備製品
4-(2-ヒドロキシ-2-プロピル)-2-プロピル-1H-イミダゾール-5-カルボン酸エチル 生産企業
Global( 506)Suppliers
| 名前 |
電話番号 |
電子メール |
国籍 |
製品カタログ |
優位度 |
|
Zhuhai Hairuide Bioscience and Technology Co., Ltd
|
+8618928027945
|
sales3@zhhairuide.com |
China |
97 |
58 |
|
ShenZhen Trendseen Biological Technology Co.,Ltd.
|
13417589054
|
trendseenbio@gmail.com |
China |
11681 |
58 |
|
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD
|
+86-576-88902229;+86-0576-88902229 +8613968687450
|
yuxin@yuxchem.com |
China |
158 |
58 |
|
Jinan Dexinjia Bio&Tech Co., Ltd
|
+86-0531-82375893 +86-15553111391
|
sales@jndxj.com |
China |
1201 |
58 |
|
Sinoway Industrial co., ltd.
|
0592-5800732; +8613806035118
|
xie@china-sinoway.com |
China |
992 |
58 |
|
Hangzhou ICH Biofarm Co., Ltd
|
+86-0571-28186870; +undefined8613073685410
|
sales@ichemie.com |
China |
985 |
58 |
|
Anhui Ruihan Technology Co., Ltd
|
+8617756083858
|
daisy@anhuiruihan.com |
China |
994 |
58 |
|
Henan Fengda Chemical Co., Ltd
|
+86-371-86557731 +86-13613820652
|
info@fdachem.com |
China |
18219 |
58 |
|
airuikechemical co., ltd.
|
+undefined86-15315557071
|
sales01@airuikechemical.com |
China |
994 |
58 |
|
hebei hongtan Biotechnology Co., Ltd
|
+86-86-1913198-3935 +8617331935328
|
sales03@chemcn.cn |
China |
952 |
58 |
144689-93-0(4-(2-ヒドロキシ-2-プロピル)-2-プロピル-1H-イミダゾール-5-カルボン酸エチル)キーワード:
- 144689-93-0
- 1H-Imidazole-4-carboxylicacid,5-(1-hydroxy-1-met
- 1H-Imidazole-5-carboxylicacid,4-(1-hydroxy-1-met
- 1H-Imidazole-4-carboxylic acid,5-(1-hydroxy-1-methylethyl)-2- propyl-,ethyl ester
- 4-(1-HYDROXY-1-METHYLETHYL)-2-PROPYL-1H-IMIDAZOLE-5-CARBOXYLIC ACID ETHYL ESTER 98+%
- 5-(1-hydroxy-1-methylethyl)-2-propyl-,ethyl ester
- 4-(1-Hydroxy-1-methylethyl)-2-propylimidazole-5-carboxylic acid ethyl ester
- 4-(1-Hydroxy-1-methylethyl)-2-propyl-
- 5-(1-hydroxy-1-Methylethyl)-2-propyl-1H-IMidazole- 4-carboxylic acid ethyl ester
- 1H-Imidazole-4-carboxylic acid, 5-(1-hydroxy-1-methylethyl)-2-propyl-, ethyl ester (9CI)
- 5-(1-Hydroxy-1-Methyl-ethyl)-2-propyl-3H-iMidazole-4-carboxylic acid ethyl ester
- Ethyl 4-(2-Hydroxy-2-propyl)-2-propyl-1H-iMidazole-5-carboxylate
- OlMesartan IMidazole Ethyl Ester IMpurity
- 1h-iMdazole-4-carboxylic acid, 5-(1-hydroxy-1-Methylethyl)-2-propyl-,ethyl ester
- 1H-IMIDAZOLE-4-CARBOXYLIC ACID-5-(1-HYDROXY-1-METHYETHYL)-2-PROPYL-ETHYL ESTER
- OlMesartan IMpurity (Ethyl 4-(1-Hydroxy-1-Methylethyl)-2- Propyl-IMidazole-5-Carboxylate)
- 4-(2-Hydroxypropan-2-yl)-2-propyl-1H-iMidazole-5-carboxylic acid ethyl ester (EPIC)
- Ethyl 4-(1-hydroxy-1-Methylethyl)-2-propyliM...
- Ethyl 4-(2-Hydroxy-2-propyl)-2-propyl-1H-imidazole-5-carboxylate
- 4-(1-Hydroxy-1-methylethyl)-2-propyl-1H-imidazole-5-carboxylic acid ethyl ester (OM-7)
- 4-(1-Hydroxy-isopropyl)-2-propyl-1H-imidazol-5-carboxylic acid ethyl ester
- Olmesartan Medoxomil Impurity 33
- Olmesartan Medoxomil-18
- OMSTint-D
- ethyl 5-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-4-carboxylate
- Olmesartan Impurity 2
- Olmesartan Impurity 50
- 4-(1-hydroxy-1-methylethyl)-2-propyl-imidazole-5-carboxylate
- Ethyl4-(2-Hydroxy-2-propyl)-2-propyl-1H-imidazole-5-carboxylate>
- 4-(1-hydroxy-1-methyL
- 4-(1-Hydroxy-1-methylethyl)-2-Propyl-1H-Imiidazole 5-Carboxylic acid ethyl ester
- 4-(2-ヒドロキシ-2-プロピル)-2-プロピル-1H-イミダゾール-5-カルボン酸エチル
- 4-(1-ヒドロキシ-1-メチルエチル)-2-プロピル-1H-イミダゾール-5-カルボン酸エチルエステル
- 4-(1-ヒドロキシ-1-メチルエチル)-2-プロピルイミダゾール-5-カルボン酸エチル