チオりん酸O-(4-ブロモ-2-クロロフェニル)O-エチルS-プロピル 化学特性,用途語,生産方法
外観
ごくうすい黄色～うすい黄色, 澄明の液体
溶解性
水に不溶 (28mg/l at25℃), 多くの有機溶剤と混和する。20mg/l 水エタノール及びアセトンに溶け、水にほとんど溶けない。
農薬用途
殺虫剤
使用上の注意
不活性ガス封入
説明
Profenofos is a pale yellow liquid, bp 100 ?C/1.80 Pa, vp
0.124 mPa (25 ?C). Solubility in water is 28 mg/L (25 ?C).
It is miscible with most organic solvents. Log Kow = 4.44.
It is relatively stable in neutral and mild acid media but
hydrolyzed in alkaline media; DT
50 values (20 ?C) at pH 5,
7, and 9 are 93 d, 14.6 d, and 5.7 h, respectively.
化学的特性
Profenofos is a pale yellow liquid. Profenofos is relatively
stable under neutral and slightly acidic conditions and unstable
under alkaline conditions.Profenofos has a garlic-like odor.
Profenofos has limited solubility in water
(28 mg/L at 25°C) but is completely soluble
in organic solvents (ethanol, acetone, toluene,
n-octanol and n-hexane) at 25°C.
使用
Profenofos is used to control insects (particularly caterpillars and
Lepidoptera eggs) and mites on cotton, maize, sugar beet, soyabean,
potatoes, vegetables, tobacco and a number of other crops
一般的な説明
Pale yellow liquid with garlic-like odor. Corrosive. Used as an insecticide.
空気と水の反応
Hydrolyzed under alkaline conditions.
反応プロフィール
Organophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.
农业用途
Profenofos: Profenofos is A U.S. EPA restricted Use Pesticide (RUP) used solely on cotton to control a number of pests including tobacco budworm, cotton aphid and bollworm, armyworm, fleahopper and whiteflies. It is not registered for residential use. Not approved for use in EU countries. Registered for use in the U.S.
製品名
CGA-15324®; CURACRON®; POLYCRON®; SELECRON®
発がん性
In a 2 year carcinogenicity study
mice were given diets containing 0, 1, 30, or 100 ppm profenofos
(equivalent to 0, 0.15, 4.5, or 15 mg/kg/day) for 85
weeks (males) or 97 weeks (females) . No treatment related clinical signs were observed. No treatment-related
gross or microscopic lesions, tumors, or biologically significant
differences in body weight or food consumption were
observed between controls and profenofos-treated animals.
Plasma and erythrocyte cholinesterase inhibition occurred at
dose levels of 4.5 and 15 mg/kg/day.
In another carcinogenicity study, rats were fed diets containing
0, 0.3, 10, or 100 ppm profenofos (equivalent to 0,
0.015, 0.5, or 5 mg/kg/day) for 2 years, and there was no
increase in tumor incidence in any treated group compared to
the control group .
環境運命予測
Plant. Dislodgable residues of profenofos on cotton leaf 0, 24, 48, 72 and 96 hours
after application (1.1 kg/ha) were 3.5, 1.1, 0.74, 0.51 and 0.35 μg/m2, respectively (Buck
et al., 1980)
Photolytic. When profenofos in an aqueous buffer solution (pH 7.0) was exposed to
filtered UV light (λ >290 nm) for 24 hours at 25 and 50°C, 29 and 61% respectively
decomposed to 4-bromo-2-chlorophenol and 4-bromo-2-chlorophenyl ethyl hydrogen
ph
Chemical/Physical. Emits toxic fumes of bromine, chlorine phosphorus and sulfur
oxides when heated to decomposition (Sax and Lewis, 1987).
代謝経路
The metabolic transformations of profenofos in plants and animals are
similar and occur via hydrolysis to 4-bromo-2-chlorophenol which is then
conjugated.
代謝
Profenofos
orally administered to rats is rapidly excreted, mainly in
the urine. The principal degradation route is hydrolysis to
4-bromo-2-chlorophenol followed by conjugation. DT
50 in
soil is about 1 week.
チオりん酸O-(4-ブロモ-2-クロロフェニル)O-エチルS-プロピル 上流と下流の製品情報
原材料
準備製品