Tigogenin
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Tigogenin 속성
- 녹는점
- 202-204°C
- 알파
- -68 º (c=0.8g/100ml, CHCl3)
- 끓는 점
- 474.91°C (rough estimate)
- 밀도
- 1.0362 (rough estimate)
- 굴절률
- 1.4700 (estimate)
- 저장 조건
- -20°C Freezer, Under inert atmosphere
- 용해도
- 클로로포름(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 15.14±0.70(Predicted)
- 색상
- 회백색
- CAS 데이터베이스
- 77-60-1(CAS DataBase Reference)
- NIST
- Tigogenin(77-60-1)
안전
| RTECS 번호 | WH1443500 |
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Tigogenin C화학적 특성, 용도, 생산
개요
Tigogenin is a steroidal sapogenin that has been found in A. sisalana and has diverse biological activities. It increases the proliferation rate of, as well as mRNA levels of genes encoding the osteoblastic differentiation markers Cbfa1, collagen type I, and osteocalcin in, mouse bone marrow stromal cells (BMSCs) in a concentration-dependent manner. It also increases matrix calcium deposition in BMSCs when used at concentrations of 30 and 90 μM. Tigogenin is active against the fungus A. fumigatus (MIC50 = 16 μg/ml). It inhibits carrageenan-induced paw edema in rats when administered at a dose of 4.2 μg/kg.화학적 성질
mp 196-208C° LOD ≤0.5%용도
Tigogenin is a saponin structurally similar to Diosgenin (D484700) and acts as a natural plant steroid which induces apoptosis in rheumatoid arthritic fibroblast-like synoviocytes.Tigogenin 준비 용품 및 원자재
원자재
준비 용품
Androst-3-ol-17-one 3-p-toluenesulfonate
3-Acetyloxy-16-methylpregna-9(11),16-dien-20-one
3-Acetyloxypregn-16-en-20-one
16-Methylpregnane-17,21-diol-3,20-dione 21-acetate
17-alpha-hydroxy-16-alpha-methyl-3,20-dioxopregna- 1,4-dien-21-yl acetate
옥시메톨론
16,17-Epoxy-3-hydroxy-16-methyl-pregn-9(11)-ene-20-one-3-acetate
3beta-hydroxy-5alpha-pregna-9(11),16-dien-20-one 3-acetate
Tigogenin 공급 업체
글로벌( 221)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21689 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 |
sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 |
ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |