D-루시페린포타슘소금

D-루시페린포타슘소금
D-루시페린포타슘소금 구조식 이미지
카스 번호:
115144-35-9
한글명:
D-루시페린포타슘소금
동의어(한글):
D-루시페린포타슘소금
상품명:
D-Luciferin potassium salt
동의어(영문):
D-Luciferin potassium;potassiuM (S)-2-(6-hydroxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylate;D-Luciferin*K;CID 135478035;D-LUCIFERIN K SALT;D-LUCIFERIN POTASSIUM S;D-Luciferenpotassiumsalt;D-LUCIFERIN POTASSIUM SAL;D-LUCIFERIN POTASSIUM SALT;D-LUCIFERINPOTASSIUMSALT,99%
CBNumber:
CB3740228
분자식:
C11H9KN2O3S2
포뮬러 무게:
320.42
MOL 파일:
115144-35-9.mol
MSDS 파일:
SDS

D-루시페린포타슘소금 속성

저장 조건
Inert atmosphere,Store in freezer, under -20°C
용해도
DMF:16.7(Max Conc. mg/mL);52.45(Max Conc. mM)
DMSO:7.5(Max Conc. mg/mL);23.55(Max Conc. mM)
Ethanol:0.25(Max Conc. mg/mL);0.79(Max Conc. mM)
PBS (pH 7.2):10.0(Max Conc. mg/mL);0.31(Max Conc. mM)
Water:32.0(Max Conc. mg/mL);100.5(Max Conc. mM)
물리적 상태
결정성 고체
색상
연노랑
BRN
5416262
InChI
InChI=1/C11H8N2O3S2.K.H/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16;;/h1-3,7,14H,4H2,(H,15,16);;/t7-;;/s3
InChIKey
UMBKGTQQGYPQBE-OGFXRTJISA-M
SMILES
C([C@H]1CSC(C2=NC3C=CC(O)=CC=3S2)=N1)(=O)O.[KH] |&1:1,r|
CAS 데이터베이스
115144-35-9(CAS DataBase Reference)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
WGK 독일 3
HS 번호 29342000
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
NFPA 704
0
2 0

D-루시페린포타슘소금 C화학적 특성, 용도, 생산

개요

D-Luciferin potassium salt(115144-35-9) is a water soluble form of D-Luciferin. D-Luciferin is a common bioluminescent substrate used for imaging of firefly luciferase expression with peak chemiluminescent emission at 560 nm. The ATP dependant luciferin oxidation is catalyzed by the Luciferase enzyme encoded by lucgene.

화학적 성질

Yellow powder

용도

D-Luciferin Potassium Salt is a class of light-emitting heterocyclic compounds found in organisms that cause bioluminescence, such as firefly. This compound creates light through the process of oxidative decarboxylation by luciferase while ATP is present. In cell culture, D-Luciferin Potassium Salt is used to achieve highly sensitive bioluminescence detection. Recently, Luciferin was used to measure the uptake of mRNA in preparation of the vaccine against COVID-19.

주요 응용

D-Luciferin may be used as a substrate in luciferase-based (EC 1.13.12.7) bioluminescence imaging and cell-based high-throughput screening applications. ATP can be measured with a reagent made up of D-luciferin and luciferase from firefly. D-Luciferin may be used and studied as a partial agonist for G protein-coupled receptor-35 (GPR35). Used for imaging the expression of the LUC marker gene and luciferase-fusion conjugates in living cells, tissues and organisms. Extensively utilized in reporter gene assays, immunoassays and hygiene monitoring.

D-루시페린포타슘소금 준비 용품 및 원자재

원자재

준비 용품


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