1,1,1,2,3,3,3-헵타플루오로프로판
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1,1,1,2,3,3,3-헵타플루오로프로판 속성
- 녹는점
- -126.8°C
- 끓는 점
- -16.4°C
- 밀도
- 1,409 g/cm3
- 굴절률
- 1.2747 (estimate)
- 용해도
- 20°C에서 물 1725분의 1에 용해됩니다.
- 안정성
- 안정적인. 강한 산화제, 알칼리 금속과 호환되지 않습니다.
- LogP
- 1.610 (est)
- CAS 데이터베이스
- 431-89-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
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안전지침서 | 23-38 | ||
유엔번호(UN No.) | 3296 | ||
위험 참고 사항 | Irritant | ||
위험 등급 | 2.2 | ||
HS 번호 | 2903460010 | ||
유해 물질 데이터 | 431-89-0(Hazardous Substances Data) | ||
독성 | mouse,LC,inhalation,> 7200gm/m3/4H (7200000mg/m3),BEHAVIORAL: MUSCLE WEAKNESSBEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)LUNGS, THORAX, OR RESPIRATION: DYSPNEA,Toksikologicheskii Vestnik. Vol. (3), Pg. 37, 1996. | ||
기존화학 물질 | 97-3-48 |
1,1,1,2,3,3,3-헵타플루오로프로판 C화학적 특성, 용도, 생산
화학적 성질
Heptafluoropropane is a liquefied gas and exists as a liquid at room temperature when contained under its own vapor pressure, or as a gas when exposed to room temperature and atmospheric pressure. The liquid is practically odorless and colorless. The gas in high concentration has a faint etherlike odor. Heptafluoropropane is noncorrosive, nonirritating, and nonflammable.용도
HFC 227ea is being developed as a CFC replacement in refrigerants, high temperature heat pumps, air-conditioning systems; as a fire suppressant; and for pharmaceutical aerosols and metered-dose inhalers.Pharmaceutical Applications
Heptafluoropropane is classified as a hydrofluorocarbon (HFC) aerosol propellant since the molecule consists only of carbon, fluorine, and hydrogen atoms. It does not contain any chlorine and consequently does not affect the ozone layer, nor does it have an effect upon global warming. It is therefore considered as an alternative propellant to CFCs for metered-dose inhalers (MDIs). While some of its physical and chemical properties are known, little has been published in regard to its use as a replacement for CFCs in MDIs.The vapor pressure of heptafluoropropane is somewhat lower than that of tetrafluoroethane and dichlorodifluoromethane but considerably higher than the vapor pressure used to formulate most MDIs.
When heptafluoropropane is used for pharmaceutical aerosols and MDIs, the pharmaceutical grade must be specified. Industrial grades may not be suitable due to their impurity profile. Similarly to tetrafluoroethane, heptafluoropropane is not a good solvent for medicinal agents or for the commonly used surfactants and dispersing agents used in the formulation of MDIs.
There are several MDIs formulated with this propellant worldwide that contain a steroid as the active ingredient.
Safety
Heptafluoropropane is used as a fire extinguisher and is applicable as a non-CFC propellant in various metered-dose inhalers. Heptafluoropropane is regarded as nontoxic and nonirritating when used as directed. No acute or chronic hazard is present when it is used normally. Inhaling high concentrations of heptafluoropropane vapors can be harmful and is similar to inhaling vapors of other propellants. Deliberate inhalation of vapors of heptafluoropropane can be dangerous and may cause death. The same labeling required of CFC aerosols would be required for those containing heptafluoropropane as a propellant (except for the EPA requirement).저장
Heptafluoropropane is a nonreactive and stable material. The liquefied gas is stable when used as a propellant and should be stored in a metal cylinder in a cool, dry place.1,1,1,2,3,3,3-헵타플루오로프로판 준비 용품 및 원자재
원자재
헥사플루오로프로필렌
불산
Heptafluoroisopropyl iodide
1,2-DICHLORO-2-IODO-1,1,2-TRIFLUOROETHANE
퍼플루오로(2,3-다이메틸부탄)
(2R, 3S) -1,2,3,4- 테트라 클로로 헥사 플루오로 부탄 1,1,2,3,4,4-, (2S, 3S)의 반응 매스 -1,2,3,4- 테트라 -1,1,2,3,4,4 - 헥사 플루오로 부탄 및 (2R, 3R) -1,2,3,4- 테트라 클로로 헥사 플루오로 부탄 1,1,2,3,4,4
트리플루오르클로로에틸렌
준비 용품
1,1,1,2,3,3,3-헵타플루오로프로판 관련 검색:
1,1,2,3,3,3-헥사플루오로-1-메톡시-2-(트라이플루오로메틸)프로페인 헵타 플루오로-1-메톡시 프로판 1,1,1,2,3,3,3-헵타플루오로프로판 과불화프로판 할로탄 프로판
2-Iodo-1,1,1,2,3,3,3-heptafluoropropane
2,3,4,5,5,5-HEXAFLUORO-2,4-BIS(TRIFLUOROMETHYL)-1-PENTANOL
3-(HEPTAFLUOROISOPROPOXY)PROPYLTRIETHOXYSILANE
2-Bromo-1,1,1,2,3,3,3-heptafluoropropane
BIS(HEPTAFLUOROISOPROPYL)KETONE
PERFLUORO-2-METHYLPENTANE
4-IODO-2-TRIFLUOROMETHYL-1,1,1,2-TETRAFLUOROBUTANE
2-chloro-1,1,1,2,3,3,3-heptafluoropropane
3-(HEPTAFLUOROISOPROPOXY)PROPYLTRICHLOROSILANE
1-IODO-4-(TRIFLUOROMETHYL)OCTAFLUOROPENT-2-ENE 97
1-Iodo-1,1,1,2,2,3,3 - Heptafluoropropane,1-Iodo-1,1,2,2,3,3,3-heptafluoropropane,3-Iodo-1,1,1,2,2,3,3-heptafluoropropane
HEPTAFLUOROPROPANE (HFC-227ea)