Tiamulin

Tiamulin 구조식 이미지
카스 번호:
55297-95-5
상품명:
Tiamulin
동의어(영문):
TIAMILIN;tiamulina;TiaMulin fuMerate API;(3aS,4R,5S,6S,8R,9R,9aR,10R)-Decahydro-8-[[2-(diethylamino)ethyl]thio]acetyloxy-5-hydroxy-4,6,9,10-tetramethyl-6-vinyl-3a,9-propano-3aH-cyclopentacycloocten-1-one;C12065;sq14055;tiavetp;iamulin;TIAMULIN;Tiamutin
CBNumber:
CB7171536
분자식:
C28H47NO4S
포뮬러 무게:
493.74
MOL 파일:
55297-95-5.mol

Tiamulin 속성

녹는점
147.5°C
끓는 점
563.0±50.0 °C(Predicted)
밀도
1.0160 (rough estimate)
굴절률
1.6550 (estimate)
저장 조건
-20°C Freezer
용해도
클로로포름(약간 용해됨), 에탄올(약간 용해됨), 메탄올(약간 용해됨)
산도 계수 (pKa)
14.65±0.70(Predicted)
색상
무색
CAS 데이터베이스
55297-95-5(CAS DataBase Reference)
EPA
Tiamulin (55297-95-5)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
WGK 독일 2
RTECS 번호 AG9552000
HS 번호 2941906000
유해 물질 데이터 55297-95-5(Hazardous Substances Data)
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H413 장기적 영향에 의해 수생생물에 유해의 우려가 있음 수생 환경유해성 물질 - 만성 구분 4
예방조치문구:
P273 환경으로 배출하지 마시오.
P501 ...에 내용물 / 용기를 폐기 하시오.

Tiamulin C화학적 특성, 용도, 생산

용도

Tiamulin is a semi–synthetic analogue of pleuromutilin in which the hydroxyacetyl side chain is replaced with a larger diethylaminoethylthioacetyl moiety, providing greater hydrophobicity and an ionisable group for salt formation and greater water solubility. Tiamulin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action. Like pleuromutilin, it inhibits protein synthesis by binding to domain V of 23S rRNA.

정의

ChEBI: A carbotricyclic compound that is pleuromutilin in which the hydroxyacetate group is replaced by a 2-{[2-(diethylamino)ethyl]sulfanyl}acetate group. An antibacterial drug, tiamulin is used in veterinary medicine (generally as its hydrogen fumarate salt) fo the treatment of swine dysentery caused by Serpulina hyodysenteriae.

Safety Profile

Poison by intramuscular and intravenous routes. Moderately toxic by ingestion and subcutaneous routes. When heated to decomposition it emits toxic fumes of SOx and NOx. See also MERCAPTANS.

Synthesis

Tiamulin was synthesized by Sandoz Co. in 1973, starting from pleuromutilin produced by Pleurotus mutilus.

Tiamulin 준비 용품 및 원자재

원자재

준비 용품


Tiamulin 공급 업체

글로벌( 192)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618740459177
sarah@tnjone.com China 1125 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21689 55
Shanxi Naipu Import and Export Co.,Ltd
+86-13734021967 +8613734021967
kaia@neputrading.com China 1011 58
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28180 58
Cangzhou Wanyou New Material Technology Co.,Ltd
18631714998
sales@czwytech.com CHINA 906 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845
sales@amoychem.com China 6387 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49391 58
SIMAGCHEM CORP
+86-13806087780
sale@simagchem.com China 17367 58
Hubei Ipure Biology Co., Ltd
+8613367258412
ada@ipurechemical.com China 10326 58
Career Henan Chemica Co
+86-0371-86658258 15093356674;
laboratory@coreychem.com China 30255 58

Tiamulin 관련 검색:

Copyright 2019 © ChemicalBook. All rights reserved