ChemicalBook >제품 카탈로그 >API>순환계 약물>항 고혈압제>5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 구조식 이미지

카스 번호:: 124750-51-2

상품명:: 5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole

동의어(영문):: Losaint-B;ALSTint-A04;Valsartan IMP;Valsartan Impurity;Valsartan Impurity 8;Valsartan Impurity 9;TRITYLATED BROMO IMP;Valsartan impurity 19;Fimasartan Impurity B;Valsartan intermediate

CBNumber:: CB8369024

분자식:: C33H25BrN4

포뮬러 무게:: 557.48

MOL 파일:: 124750-51-2.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 544

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 속성

녹는점: 152-155°C

끓는 점: 61°C/12mmHg(lit.)

밀도: 1.28±0.1 g/cm3(Predicted)

저장 조건: Inert atmosphere,2-8°C

용해도: Soluble in Chloroform and Methanol (Sparingly)

물리적 상태: Solid

산도 계수 (pKa): 0.29±0.10(Predicted)

색상: White

안정성: 수분에 민감한

InChI: InChI=1S/C33H25BrN4/c34-24-25-20-22-26(23-21-25)30-18-10-11-19-31(30)32-35-36-37-38(32)33(27-12-4-1-5-13-27,28-14-6-2-7-15-28)29-16-8-3-9-17-29/h1-23H,24H2

InChIKey: ZTFVTXDWDFIQEU-UHFFFAOYSA-N

SMILES: N1(C(C2=CC=CC=C2)(C2=CC=CC=C2)C2=CC=CC=C2)C(C2=CC=CC=C2C2=CC=C(CBr)C=C2)=NN=N1

CAS 데이터베이스: 124750-51-2(CAS DataBase Reference)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

유엔번호(UN No.)	UN 2811 6.1/PG III
위험 등급	6.1
포장분류	III

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H228	인화성 고체	인화성 고체	구분 1 구분 2	위험 경고	P210, P240,P241, P280, P370+P378
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H319	눈에 심한 자극을 일으킴	심한 눈 손상 또는 자극성 물질	구분 2A	경고	P264, P280, P305+P351+P338,P337+P313P

예방조치문구:

P210	열·스파크·화염·고열로부터 멀리하시오 - 금연 하시오.
P240	용기와 수용설비를 접지 및 접합시키시오.
P241	폭발 방지용 장비[전기적/환기/조명/...]을(를) 사용하시오.
P264	취급 후에는 손을 철저히 씻으시오.
P264	취급 후에는 손을 철저히 씻으시오.
P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P302+P352	피부에 묻으면 다량의 물로 씻으시오.
P305+P351+P338	눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
P332+P313	피부 자극이 생기면 의학적인 조치· 조언을 구하시오.
P337+P313	눈에 대한 자극이 지속되면 의학적인 조치· 조언를 구하시오.
P370+P378	화재 시 불을 끄기 위해 (Section 5. 폭발, 화재시 대처방법의 적절한 소화제)을(를) 사용하시오.

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole C화학적 특성, 용도, 생산

화학적 성질

Off-White Solid

용도

Used as Olmesartan medoxomil related intermediate, Olmesartan medoxomil is an angiotensin II receptor antagonist^[1].

주요 응용

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole is an important pharmaceutical intermediate. It can be used in the preparation of olmesartan medoxomil key intermediates, Losartan potassium, Valsartan, Candesartan and molecular sieve catalysts.

위험도

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole has an acute toxin and is irritating to skin and eyes.

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 준비 용품 및 원자재

원자재

준비 용품

트리틸올메사르탄 Ethyl-2-Ethoxy-1-[[(2'-(1h-Tetrazol-5-Yl)Biphenyl-4-Yl)Methyl]Benzimidazole]-7-Carboxylate 1H-IMidazole-5-carboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester 1H-Imidazole-4,5-dicarbonitrile, 2-butyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]- diethyl 2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-4,5-dicarboxylate 2-Butyl-4-chloro-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxaldehyde

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 공급 업체

글로벌( 544)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Sinopharm International Guangzhou Ltd.	+86-2038033341 +86-18520036739	zhuluqiang@sinopharm.com	China	77	58
JUYE XIANDAI fine chemistry Co.,Ltd	+86-18958038633; +8618958038633	tony@sdhypharma.com	China	64	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12470	58
Hebei Dangtong Import and export Co LTD	+8615632927689	admin@hbdangtong.com	China	984	58
Hangzhou ICH Biofarm Co., Ltd	+86-0571-28186870; +undefined8613073685410	sales@ichemie.com	China	985	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15954	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21687	55
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55

5-(4'-Bromomethyl-1,1'-biphenyl-2-yl)-1-triphenylmethyl-1H-tetrazole 관련 검색:

데카브로모디페닐에테르 폴리브로민산염 바이페닐(폴리브로민산염 비페닐) 비페닐 염화 2,3,5-트리페닐 테트라졸륨 4,4'-Dimethylbiphenyl 2-Bromobiphenyl 4-(1-Methoxy-1-methylethyl)-2-propyl-1H-Imidazole-5-carboxylic acid ethyl ester 2-(2-butyl-4-Methyl-6-oxo-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-1,6-dihydropyriMidin-5-yl)-N,N-diMethylethanethioaMide METHYL TRIPHENYLMETHYL ETHER 2-(1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)Methyl)-2-butyl-4-Methyl-6-oxo-1,6-dihydropyriMidin-5-yl) -N,N-diMethylacetaMide Fimasartan 2-Butyl-1,6-dihydro-N,N,4-trimethyl-6-oxo-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-5-pyrimidineacetamide 2-(2-butyl-4-hydroxy-6-MethylpyriMidin-5-yl)-N,N-diMethylacetaMide OlMesartan MedoxoMil iMpurity V N-Trityl Olmesartan Ethyl Ester Diethyl 2-propylImidazoledicarbonate OlMesartan MedoxoMil Butyl IMpurity 4,5-Dimethyl-1,3-dioxol-2-one