Anthranilic acid can be used in organic synthesis to generate the benzyne intermediate. It is used as an intermediate for production of dyes, pigments, and saccharin. It and its esters are used in preparing perfumes to imitate jasmine and orange, pharmaceuticals and UV-absorber as well as corrosion inhibitors for metals and mold inhibitors in soya sauce.
정의
ChEBI: An aminobenzoic acid that is benzoic acid having a single amino substituent located at position 2. It is a metabolite produced in L-tryptophan-kynurenine pathway in the central nervous system.
주요 응용
2-Aminobenzoic acid is called vitamin L1; it enhances the milk production of cows. The major use of 2-aminobenzoic acid is as an intermediate for dyes. As its occurrence suggests, it is an intermediate for indigo synthesis. Mordant Brown 40 and Vat Violet 13 are other derivatives. 4-Hydroxy-1-methyl-carbostyril [1677- 46-9] is an important derivative used in making dyes and pigments. Its methyl and ethyl esters are used as fragrances for toiletries. In the pharmaceutical industry, it is used as an intermediate for tranquilizers and antiphlogistics.
일반 설명
Odorless white to pale-yellow or tan crystalline powder with a sweetish taste.
공기와 물의 반응
Anthranilic acid may be sensitive to prolonged exposure to air and light. Insoluble in water.
반응 프로필
Anthranilic acid is incompatible with strong oxidizers.
위험도
Questionable carcinogen.
화재위험
Anthranilic acid is combustible.
Safety Profile
Moderately toxic by
ingestion and intraperitoneal routes.
Experimental reproductive effects. Human
mutation data reported. Questionable
carcinogen with experimental tumorigenic
data. Combustible. When heated to
decomposition it emits toxic fumes of NOx.
Purification Methods
Crystallise anthranilic acid from water (charcoal). It has also been recrystallised from 50% aqueous acetic acid. It sublimes in a vacuum. [Beilstein 14 IV 1004.]
