(S)-3-하이드록시피롤리딘
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(S)-3-하이드록시피롤리딘 속성
- 녹는점
- 15°C
- 끓는 점
- 108-110 °C (8 mmHg)
- 알파
- -6.5 º (c=3.5% in MeOH)
- 밀도
- 1.078 g/mL at 20 °C (lit.)
- 굴절률
- n
20/D 1.490
- 인화점
- >110°C
- 저장 조건
- 2-8°C
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 산도 계수 (pKa)
- 14.91±0.20(Predicted)
- 물리적 상태
- 녹은 후에 액체
- 색상
- 맑은 노란색에서 노란색까지
- Specific Gravity
- 1.078
- optical activity
- [α]20/D 6.5±1.5°, c = 3.5% in methanol
- 수용성
- 물에 완전히 섞임.
- 감도
- Air Sensitive & Hygroscopic
- BRN
- 4652606
- CAS 데이터베이스
- 100243-39-8(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi,Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-40 | ||
| 안전지침서 | 26-37/39-36-22 | ||
| WGK 독일 | 3 | ||
| F 고인화성물질 | 10-34 | ||
| HS 번호 | 29339900 |
(S)-3-하이드록시피롤리딘 C화학적 특성, 용도, 생산
개요
(S)-3-Hydroxypyrrolidine is a chiral organic compound that serves as an important building block in the synthesis of various pharmaceuticals and natural products. It is a four-membered heterocyclic amino alcohol, featuring a hydroxyl group and a stereogenic center. The 'S' prefix indicates the configuration at the stereocenter, which is crucial for its reactivity and biological activity. This compound is notable for its role as an intermediate in the synthesis of drugs, particularly those targeting the central nervous system. The enantiomeric purity of (S)-3-Hydroxypyrrolidine is often critical, as the 'R' and 'S' enantiomers can exhibit different pharmacological properties.화학적 성질
clear light yellow to yellow liquid after melting용도
(S)-(-)-3-Hydroxypyrrolidine is an important raw material and intermediate used in organic synthesis, pharmaceuticals agrochemicals and dyestuff fields.Purification Methods
The (±)-isomer is purified by repeated distillation ( b 102-104o/12mm, 108-110o/18mm), and the (±)-picrate crystallises from EtOH with m 140-141o. The R(+)-enantiomer has b 70o/0.6mm and [] D +5.6o (c 3.63, MeOH). Its hydrochloride has a negative rotation and its dimethiodide has m 230o and [] 24 -8.02o. [Suyama & Kanno Yakugaku Zasshi (J Pharm Soc Japan) 85 531 1965, Uno et al. J Heterocycl Chem 24 1025 1987, Flanagan & Joullie Heterocycles 26 2247 1987, Beilstein 21 III/IV 44.](S)-3-하이드록시피롤리딘 준비 용품 및 원자재
원자재
준비 용품
(S)-3-하이드록시피롤리딘 공급 업체
글로벌( 308)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| SyncoZymes (Shanghai) Co., Ltd., | +86-021-68187180-811 +86-13681683526 |
lchen@syncozymes.com | China | 188 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 6011 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Anhui Dexinjia Biopharm Co., Ltd | +86-531-82375818 +8615064153060 |
alice@jndxj.com | China | 292 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 7154 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49391 | 58 |
| Richest Group Ltd | 18017061086 |
oled@richest-group.com | CHINA | 5601 | 58 |
(S)-3-하이드록시피롤리딘 관련 검색:
N-메틸-2-피롤리디논 피롤리딘 폴리비닐피로리돈 2-피로리딘온,1-에테닐-
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(S)-1-Benzyl-3-pyrrolidinol
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Scopine hydrochloride
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HYOSCINE HYDROCHLORIDE
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SCOPOLAMINE N-OXIDE HYDROBROMIDE
METHYL-2-PYRROLIDONE
SAXITOXIN