Granisetron hydrochloride is the second selective 5HT-3-antagonist approved for the
management of nausea and vomiting induced by cancer chemotherapy.Like
ondansetron, granisetron hydrochloride is superior to metoclopramide in both efficacy
and side effect profile. The compound appears to be effective both as a prophylactic
agent and in blocking vomiting once started.
화학적 성질
White to Off-White Crystalline Sold
용도
A specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemothera
py. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarini
c receptor
일반 설명
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
생물학적 활성
5-HT 3 receptor antagonist that possesses potent antiemetic activity.
