O-페닐렌다이아민
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O-페닐렌다이아민 속성
- 녹는점
- 100-102 °C
- 끓는 점
- 256-258 °C
- 밀도
- 1,27 g/cm3
- 증기 밀도
- 3.7 (vs air)
- 증기압
- 0.01 mm Hg ( 25 °C)
- 굴절률
- 1.6339 (estimate)
- 인화점
- 110°C
- 저장 조건
- 2-8°C
- 용해도
- H2O: 1정/10mL, 투명, 무색
- 물리적 상태
- 태블릿 형태
- 색상 색인 번호
- 76010
- 산도 계수 (pKa)
- 4.46(at 25℃)
- 색상
- 흰색에서 황백색까지
- pH 범위
- Green Q uorescence (3.1) to nonQ uorescence (4.4)
- 수소이온지수(pH)
- 7-8 (50g/l, H2O, 20℃)
- 폭발한계
- 1.5%(V)
- 수용성
- 20°C에서 <0.1g/100mL
- 감도
- Air & Light Sensitive
- Merck
- 14,7284
- BRN
- 606074
- 노출 한도
- TLV-TWA 0.1 mg/m3; carcinogenicity: A2- Suspected Human Carcinogen (ACGIH 1989).
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다.
- 주요 응용
- bottom antireflective coatings, semiconductor devices, hair dyes, detecting antibody, substrate for horseantibody, glucose, streptomycin, penicillin, sulfonamide, neuroglobin, substrate for horseradish peroxidase
- LogP
- 0.12-0.17 at 20-25℃ and pH7-8
- CAS 데이터베이스
- 95-54-5(CAS DataBase Reference)
- IARC
- 2B (Vol. 123) 2020
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T,N | ||
---|---|---|---|
위험 카페고리 넘버 | 20/21-25-36-40-43-50/53-68 | ||
안전지침서 | 28-36/37-45-60-61-1/2 | ||
유엔번호(UN No.) | UN 1673 6.1/PG 3 | ||
WGK 독일 | 3 | ||
RTECS 번호 | SS7875000 | ||
F 고인화성물질 | 8-10-23 | ||
자연 발화 온도 | 540 °C | ||
TSCA | Yes | ||
위험 등급 | 6.1 | ||
포장분류 | III | ||
HS 번호 | 29215119 | ||
유해 물질 데이터 | 95-54-5(Hazardous Substances Data) | ||
독성 | LD50 in rats (mg/kg): 1070 orally; 516 i.p., C. Burnett et al., J. Toxicol. Environ. Health 2, 657 (1977) | ||
기존화학 물질 | KE-02174 | ||
유해화학물질 필터링 | 97-1-334 | ||
함량 및 규제정보 | 물질구분: 유독물질; 혼합물(제품)함량정보: 페닐렌디아민과 그 염류 및 이를 25% 이상 함유한 혼합물 |
O-페닐렌다이아민 C화학적 특성, 용도, 생산
화학적 성질
o-Phenylenediamine is a white to brownish crystalline substance that turns red upon exposure to air.용도
o-Phenylenediamine is an amino substituted benzene used in the manufacture of dyes. Potential use in sensitive immunosensor for cancer biomarker.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.정의
ChEBI: A phenylenediamine in which the two amino groups are ortho to each other.일반 설명
Colorless monoclinic crystals if pure; technical grade brownish-yellow crystals or a sandy brown solid. Used in manufacture of dyes, photography, organic synthesis.공기와 물의 반응
Soluble in water [Hawley]. Melting point 219 F. Flash point 277 F. Toxic by skin absorption, inhalation or ingestion. Even as a solid will spot downwind area brown/purple (Roger Patrick, DuPont Engineer).반응 프로필
o-Phenylenediamine a weak aromatic amine base neutralizes acids in exothermic reactions to form salts. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Darkens on exposure to air (Roger Patrick, DuPont Engineer).건강위험
The toxic effects of m-phenylenediamineare similar to its ortho- and para-isomers.The toxic symptoms were tremor, excite ment, convulsions, and cyanosis, and col lapse at fatal dose. Other symptoms includeddecreased blood pressure and pulse rate.Chronic toxic effects resulting from the oralapplication of an aqueous solution of thiscompound were increase in liver and to alesser extent, kidney weights. No carcinogenicity was observed in test animals. Thecompound was excreted rapidly, unchanged.LD50 value, oral (rats): 650 mg/kg.
화재위험
Flash point data for o-Phenylenediamine are not available. o-Phenylenediamine is probably combustible.Safety Profile
Confirmed carcinogen. Poison by ingestion and intraperitoneal routes. Moderately toxic by subcutaneous route. Mildly toxic by skin contact. Mutation data reported. A pesticide and pharmaceutical. When heated to decomposition it emits toxic fumes of NOx. See also other phenylenediamine entries and AMINES잠재적 노출
Used as an intermediate in the making of dyes; pesticides, pharmaceuticals, and rubber chemicals; in making fungicides and other chemicals; in photographic and analytical procedures and processesCarcinogenicity
o-PDA (dihydrochloride) induced hepatocellular carcinomas during an 18-month feeding study in male Charles River CD rats given diets containing 2000 or 4000 ppm of the chemical (female rats not used in this study). No significant carcinogenic effects were observed in male and female CD-1 mice given higher doses (6872 or 13,743 ppm) of the compound.운송 방법
UN1673 Phenylenediamines (o-, m-, p-), Hazard Class: 6.1; Labels: 6.1-Poisonous materials.Purification Methods
Crystallise the diamine from aqueous 1% sodium hydrosulfite (charcoal), wash it with ice-water and dry it in a vacuum desiccator, or sublime it in vacuo. It has been purified by recrystallisation from toluene and zone refined [Anson et al. J Am Chem Soc 108 6593 1986]. Purification by refluxing a CH2Cl2 solution containing charcoal is also carried out followed by evaporation and recrystallisation [Koola & Kochi J Org Chem 52 4545 1987], protect from light. The acetate has m 186o. [Beilstein 13 IV 38.]비 호환성
Dust may form explosive mixture with air. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, acid chlorides; acid anhydrides; chloroformates. Heat and light contribute to instability. Keep away from metals; 1,2-PHENYLENEDIAMINE a weak aromatic amine base neutralizes acids in exothermic reactions to form salts. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Darkens on exposure to air (Roger Patrick, DuPont Engineer).폐기물 처리
Controlled incineration whereby oxides of nitrogen are removed from the effluent gas by scrubber, catalytic or thermal device.O-페닐렌다이아민 준비 용품 및 원자재
원자재
준비 용품
4-QUINOXALIN-2-YLPHENOL
1H-Benzimidazole-2-methanol
Quinoxaline
Methylcyanocarbamate
2-(a-Hydroxyethyl)benzimidazole
(1-METHYL-1H-BENZIMIDAZOL-2-YL)METHYLAMINE
2-(2-PYRIDYL)BENZIMIDAZOLE
2-퀴노자린카르복실산
2,3-피라진디카르복실릭 안하이드라이드
Oxatomide
2-Benzimidazolecarboxylic acid
2'-AMINOACETANILIDE
2-QUINOXALINETHIOL
QUINTIOPHOS
Oxfendazole
O-페난트롤린
FUBERIDAZOLE
Sodium benzotriazole
2-Methylbenzimidazole
1H-BENZOIMIDAZOLE-2-THIOL
Vat Red 14
2-(DICHLOROMETHYL)BENZIMIDAZOLETHIOL
dispersant BZS
BASIC YELLOW 40
Vat Brown B
티오판산-메틸
ETHYL 2-QUINOXALINECARBOXYLATE
2,3-DIHYDROXYQUINOXALINE-6-CARBOXYLIC ACID
3-METHYL-2-QUINOXALINOL
5,12-DIHYDRO-5,7,12,14-TETRAZAPENTACENE
오메프라졸
Bendazol
4-bromo-2,1,3-benzothiadiazole
2-메르캅토 벤즈이미다졸
2-CHLORO-3-METHYL-QUINOXALINE
3-AMINO-PHENAZIN-2-OL
1H-BENZIMIDAZOLE-2-CARBONYL CHLORIDE HYDROCHLORIDE
메틸퀴녹스알린
2,3-DIAMINOPHENAZINE
QUINOXALINE-2,3-DICARBOXYLIC ACID
O-페닐렌다이아민 공급 업체
글로벌( 558)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Masteam Bio-tech Co., Ltd. | +86-15200345168 +86-15200345168 |
bruce.lei@masteam.com | CHINA | 153 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 |
sales@molcore.com | China | 49739 | 58 |
Guangzhou Tosun Pharmaceutical Limited | +8618922120635 |
sales@toref-standards.com | China | 1000 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12471 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 6000 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21689 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9341 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32686 | 60 |