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ChemicalBook >> CAS DataBase List >> SU 5416

SU 5416

SU 5416 price.
  • $23 - $972
  • Product name: SU 5416
  • CAS: 204005-46-9
  • MF: C15H14N2O
  • MW: 238.28
  • EINECS:200-256-5
  • MDL Number:MFCD01940922
  • Synonyms:H-Indol-2-one, 3-((3,5-dimethyl-1H-pyrrol-2-yl)methylene)-1,3-dihydro-;SeMaxinib;SU 5416 (SeMaxinib);SU5416 /SU-5416;(Z)-3-((3,5-diMethyl-1H-pyrrol-2-yl)Methylene)indolin-2-one;3-((3,5-diMethyl-1H-pyrrol-2-yl)Methylene)indolin-2-one;3-[(3,5-diMethyl-1H-pyrrol-2-yl)Methylidene]-1H-indol-2-one;SEMAXINIB(SU 5416)
36 prices
Selected condition:
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
  • TRC
Package
  • 10mM(in 1mL DMSO)
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 0.25G
  • 250mg
  • 500MG
  • 1g
  • ManufacturerAK Scientific
  • Product number2033AH
  • Product descriptionSemaxanib
  • Packaging5mg
  • Price$91
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA325242
  • Product descriptionSU 5416 98+%
  • Packaging5mg
  • Price$30
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA325242
  • Product descriptionSU 5416 98+%
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA325242
  • Product descriptionSU 5416 98+%
  • Packaging50mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA325242
  • Product descriptionSU 5416 98+%
  • Packaging100mg
  • Price$169
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA325242
  • Product descriptionSU 5416 98+%
  • Packaging1g
  • Price$421
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA325242
  • Product descriptionSU 5416 98+%
  • Packaging250mg
  • Price$421
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000244
  • Product descriptionSU 5416 95.00%
  • Packaging5MG
  • Price$193.6
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000244
  • Product descriptionSU 5416 95.00%
  • Packaging500MG
  • Price$578
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberKIN0000244
  • Product descriptionSU 5416 95.00%
  • Packaging0.25G
  • Price$876
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3847
  • Product descriptionSU 5416
  • Packaging10mM(in 1mL DMSO)
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3847
  • Product descriptionSU 5416
  • Packaging10mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3847
  • Product descriptionSU 5416
  • Packaging50mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3847
  • Product descriptionSU 5416
  • Packaging100mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS521318
  • Product descriptionSU 5416 ≥98%
  • Packaging5mg
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS521318
  • Product descriptionSU 5416 ≥98%
  • Packaging10mg
  • Price$30
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 2033AH Semaxanib 5mg $91 2021-12-16 Buy
Ambeed A325242 SU 5416 98+% 5mg $30 2021-12-16 Buy
Ambeed A325242 SU 5416 98+% 10mg $50 2021-12-16 Buy
Ambeed A325242 SU 5416 98+% 50mg $50 2021-12-16 Buy
Ambeed A325242 SU 5416 98+% 100mg $169 2021-12-16 Buy
Ambeed A325242 SU 5416 98+% 1g $421 2021-12-16 Buy
Ambeed A325242 SU 5416 98+% 250mg $421 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000244 SU 5416 95.00% 5MG $193.6 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000244 SU 5416 95.00% 500MG $578 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000244 SU 5416 95.00% 0.25G $876 2021-12-16 Buy
ApexBio Technology A3847 SU 5416 10mM(in 1mL DMSO) $60 2021-12-16 Buy
ApexBio Technology A3847 SU 5416 10mg $70 2021-12-16 Buy
ApexBio Technology A3847 SU 5416 50mg $190 2021-12-16 Buy
ApexBio Technology A3847 SU 5416 100mg $250 2021-12-16 Buy
Arctom AS521318 SU 5416 ≥98% 5mg $23 2021-12-16 Buy
Arctom AS521318 SU 5416 ≥98% 10mg $30 2021-12-16 Buy

Properties

Melting point :226-228 °C
Boiling point :481.4±45.0 °C(Predicted)
Density :1.256±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :H2O: insoluble
pka :12.59±0.20(Predicted)
form :Yellow orange solid
color :yellow to yellow orange

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.

Description

SU 5416 is a tyrosine kinase inhibitor best known as an inhibitor of the vascular endothelial growth factor receptor (VEGFR2; FLK1/KDR) and a suppressor of tumor vascularization, preventing the growth of multiple tumor types. In addition to inhibiting VEGFR2 (IC50 = 1 μM), SU 5416 also inhibits PDGFR (IC50 = 20 μM), c-Kit (IC50 = 30 nM), RET (IC50 = 170 nM), FLT3 (IC50 = 160 nM), ABL (IC50 = 11 μM), and ALK (IC50 = 1.2 μM). SU 5416 does not inhibit epidermal growth factor or fibroblast growth factor receptor tyrosine kinases (IC50 > 100 μM).

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