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ChemicalBook >> CAS DataBase List >> polyethyleneimine

polyethyleneimine

polyethyleneimine price.
  • $100 - $556
  • Product name: polyethyleneimine
  • CAS: 25987-06-8
  • MF: C4H13N3
  • MW: 103.17
  • EINECS:247-038-6
  • MDL Number:MFCD00084427
  • Synonyms:PolyethyleniMine, ethylenediaMine branched average Mw ~800 by LS, average Mn ~600 by GPC;Polyethylenimine, ethylenediamine branched;POLYETHYLENIMINE LOW MOLECULAR WEIGHT;1,2-Ethanediamine,polymerwithaziridine ;Polyethylenimine, branched average Mw ~800 by LS, average Mn ~600 by GPC;Polyethylenimine solution;Polyethylenimine, epichlorohydrin modified solution;BRANCHED POLYMER
4 prices
Selected condition:
Brand
  • Sigma-Aldrich
  • TRC
Package
  • 25g
  • 100ml
  • 250ml
  • 1l
  • ManufacturerSigma-Aldrich
  • Product number408719
  • Product descriptionPolyethylenimine, ethylenediamine branched average Mw ~800 by LS, average Mn ~600 by GPC
  • Packaging100ml
  • Price$109
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number408719
  • Product descriptionPolyethylenimine, ethylenediamine branched average Mw ~800 by LS, average Mn ~600 by GPC
  • Packaging250ml
  • Price$229
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number408719
  • Product descriptionPolyethylenimine, ethylenediamine branched average Mw ~800 by LS, average Mn ~600 by GPC
  • Packaging1l
  • Price$556
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberP688508
  • Product descriptionPolyethylenimine(Branched)(TechnicalGrade)
  • Packaging25g
  • Price$100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 408719 Polyethylenimine, ethylenediamine branched average Mw ~800 by LS, average Mn ~600 by GPC 100ml $109 2024-03-01 Buy
Sigma-Aldrich 408719 Polyethylenimine, ethylenediamine branched average Mw ~800 by LS, average Mn ~600 by GPC 250ml $229 2024-03-01 Buy
Sigma-Aldrich 408719 Polyethylenimine, ethylenediamine branched average Mw ~800 by LS, average Mn ~600 by GPC 1l $556 2024-03-01 Buy
TRC P688508 Polyethylenimine(Branched)(TechnicalGrade) 25g $100 2021-12-16 Buy

Properties

Density :1.08 g/mL at 25 °C
vapor pressure :9 mm Hg ( 20 °C)
refractive index :n20/D 1.5240
Flash point :>230 °F
solubility :Chloroform (Sparingly), DMSO (Sparingly), Methanol (Slightly)
form :Oil
color :Colourless
InChI :InChI=1S/C2H8N2.C2H5N/c3-1-2-4;1-2-3-1/h1-4H2;3H,1-2H2
InChIKey :SFLOAOINZSFFAE-UHFFFAOYSA-N
SMILES :C(N)CN.C1NC1
EPA Substance Registry System :1,2-Ethanediamine, polymer with aziridine (25987-06-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H411 Toxic to aquatic life with long lasting effects Hazardous to the aquatic environment, long-term hazard Category 2
Precautionary statements:
P273 Avoid release to the environment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.

Description

Polyethylenimine (PEI) is a polycationic molecule that has been shown to produce efficient gene transfection in numerous cell lines in vitro without the need for an endo- somolytic agent (Fig. 1). Every third atom of PEI is a nitrogen atom, leading to a densely positively charged backbone necessary for an efficacious DNA binding. PEI enhances the cellular endocytosis of plasmids but also facil-itates their endosomal escape by buffering the endosomal compartments, leading to lysosomal osmotic swelling and disruption. Although PEI is an efficient gene transfer polymer in vitro, its cytotoxicity needs to be improved for widening its use in vivo. Used as a polyelectrolyte multilayer on charged surfaces to provide a biocompatible coating on surfaces.
Chemical structure of polymers used for gene delivery.
Fig. 1 Chemical structure of polymers used for gene delivery.

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