347396-82-1 Basic information More..
Product Name:Ranibizumab
Synonyms:Lucentis;Ranibizumab;Unii-zl1R02vt79;Ranibizumab - 25mg/ml solution in PBS;Ranibizumab USP/EP/BP;RanibizumabQ: What is Ranibizumab Q: What is the CAS Number of Ranibizumab Q: What is the storage condition of Ranibizumab;Research Grade Ranibizumab(DHD12601);Ranibizumab (anti-VEGF)
CAS:347396-82-1
MF:C11H12N2O2
MW:204.22518
EINECS:
Mol File:347396-82-1.mol
347396-82-1

Use

Ranibizumab is a recombinant, humanized, IgG1 monoclonal antibody fragment (Fab) that neutralizes all active forms of vascular endothelial growth factor A (VEGF-A), and it is indicated for the treatment of neovascular age-related macular degeneration (AMD). It consists of a nonbinding human sequence and a high-affinity binding epitope (Fab fragment) derived from the mouse. The full-length RhuMab VEGF (bevacizumab) was launched previously by Genentech for the treatment of colorectal cancer. Both the antibody fragment and the full-length antibody bind to and inhibit all active forms of VEGF-A and are derived from the same mouse monoclonal antibody. However, ranibizumab has been genetically engineered through a process of selective mutation to increase its affinity for binding and inhibiting the growth factor.

Ranibizumab manufacturers

  • Ranibizumab
  • US $0.00 / kg
  • 2024-05-24
  • CAS:347396-82-1
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10000kg
  • Ranibizumab
  • US $0.00-0.00 / mg
  • 2021-09-16
  • CAS:347396-82-1
  • Min. Order: 5mg
  • Purity: 99%
  • Supply Ability: 100KG
  • Ranibizumab
  • US $10.00 / KG
  • 2021-08-31
  • CAS:347396-82-1
  • Min. Order: 1KG
  • Purity: 99.99%
  • Supply Ability: 20 tons/month
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