| | 961-07-9 Basic information More.. |
| Product Name: | 2'-Deoxyguanosine | | Synonyms: | DEOXYGUANOSINE-2';GUANINE DESOXYRIBOSIDE;2'-DEOXY-D-GUANOSINE;A-2'-DEOXYGUANOSINE;9-(2'-DEOXY-BETA-D-RIBOFURANOSYL)GUANINE;2(acute)-Deoxyguanosine;2-amino-9-(4-hydroxy-5-methylol-tetrahydrofuran-2-yl)-3H-purin-6-one;2-amino-9-[4-hydroxy-5-(hydroxymethyl)-2-tetrahydrofuranyl]-3H-purin-6-one | | CAS: | 961-07-9 | | MF: | C10H13N5O4 | | MW: | 267.24 | | EINECS: | 213-505-8 | | Mol File: | 961-07-9.mol |  |
Use
2'-Deoxyguanosine monohydrate (Deoxyguanosine; dG) is composed of the purine nucleoside guanine linked by its N9 nitrogen to the C1 carbon of deoxyribose. It is a purine nucleoside that upon sequential phosphoylation (kinases) forms dGTP which is used by DNA polymerases and reverse transcriptases to synthesis DNA(s). Deoxyguanosine is the most electron rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.
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961-07-9
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