3930-20-9 Basic information More..
Product Name:Sotalol
Synonyms:SOTALOL;4'-[1-Hhydroxy-2-(isopropylamino)ethyl]methanesulfonanilide;4'-[1-Hydroxy-2-(isopropylamino)ethyl]metahnesulfonanilide;4'-[1-Hydroxy-2-(isopropylamino)ethyl]methanesulfonanilide;4’-(1-hydroxy-2-(isopropylamino)ethyl)-methanesulfonanilid;4’-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilide;beta-Cardone;dl-sotalol
CAS:3930-20-9
MF:C12H20N2O3S
MW:272.36
EINECS:
Mol File:3930-20-9.mol
3930-20-9

Use

The sotalol enantiomers produce different effects onthe heart. Class III action of d-sotalol in the sinus node isassociated with slowing of sinus heart rate, whereas -adrenergicblockade contributes to the decrease in heart rate observedwith 1- or d,1-sotalol. Sotalol is not metabolized, noris it bound significantly to proteins. Elimination occurs byrenal excretion, with more than 80% of the drug eliminatedunchanged. Sotalol is characteristic of class III antiarrhythmicdrugs, in that it prolongs the duration of the action potentialand, thus, increases the effective refractory period of myocardialtissue. It is distinguished from the other class III drugs(amiodarone and bretylium) because of its -adrenergicreceptor–blocking action.

Sotalol manufacturers

  • Sotalol
  • US $0.00-0.00 / g
  • 2023-11-03
  • CAS:3930-20-9
  • Min. Order: 1g
  • Purity: 99%
  • Supply Ability: 100000tons
  • Sotalol
  • US $90.00-70.00 / kg
  • 2023-10-20
  • CAS:3930-20-9
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10000/month
  • Sotalol
  • US $90.00-70.00 / kg
  • 2023-10-20
  • CAS:3930-20-9
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10000/month
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