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Thioguanine

Thioguanine Suppliers list
Company Name:   
Tel:
Email: alsindialife@gmail.com
Products Intro: Cas:154-42-7
ProductName:Thioguanine
Purity: 98% | Package: 1 kg,5 kg, 10 kg,25kg and 1 MT
Company Name: Shanghai?Medlife?Pharm-Tech?Co.,?Ltd  
Tel: 021-59167510 18117107507
Email: vip@med-life.cn
Products Intro: Cas:154-42-7
ProductName:Thioguanine
Purity: >=98% | Package: 500mg;50mg
Company Name: Wuhan woxuan Technology Co., Ltd  
Tel: 13322067656
Email: 392306494@qq.com
Products Intro: Cas:154-42-7
ProductName:Thioguanine
Purity: 99% HPLC | Package: 5KG;1KG;25kg;500kg
Company Name: QUALITY CONTROL SOLUTIONS LTD.  
Tel: 13670046396
Email: sales@chem-strong.com
Products Intro: Cas:154-42-7
ProductName:Thioguanine
Purity: 95% HPLC | Package: 10MG;25MG;50MG;100MG
Company Name: https://www.shachemlin.cn/  
Tel: 021-68080707 15021879576
Email: catherine@chemlin.com.cn
Products Intro: Cas:154-42-7
ProductName:Thioguanine
Purity: 99% | Package: 10g;50g;500g

Thioguanine manufacturers

  • 6-Thioguanine
  • 6-Thioguanine pictures
  • $0.00 / 1KG
  • 2023-09-06
  • CAS:154-42-7
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 500000kg
  • 6-Thioguanine
  • 6-Thioguanine pictures
  • $10.70 / 1g/Bag
  • 2023-03-06
  • CAS:154-42-7
  • Min. Order: 10g
  • Purity: 99%
  • Supply Ability: 10000kg
  • 6-Thioguanine
  • 6-Thioguanine pictures
  • $0.00 / 25kg
  • 2023-01-14
  • CAS:154-42-7
  • Min. Order: 1kg
  • Purity: 98%min
  • Supply Ability: 1000kg
Thioguanine Basic information
Product Name:Thioguanine
Synonyms:2-Amino-1,7(9)-dihydro-purine-6-thione;2-amino-6-mercaptopurine (50X)*gamma-irradiated C;2-amino-6-mercaptopurine crystalline;2-Amino-6-purinethiol (6-Thioguanine);2-AMINO-6-MERCAPTOPURINE (50X)GAMMA-IRRA DIATED CEL;Tioguanine(Thioguanine);6-Thioguanine,~97%;6-THIOGUANIDE
CAS:154-42-7
MF:C5H5N5S
MW:167.19
EINECS:205-827-2
Product Categories:TABLOID;Nucleosides, Nucleotides & Related Reagents;Inhibitor;Bases & Related Reagents;Nucleotides;Sulfur & Selenium Compounds;Antitumors for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleobases and their analogs;Purine;All Inhibitors;Purines;Pyridines, Pyrimidines, Purines and Pteredines
Mol File:154-42-7.mol
Thioguanine Structure
Thioguanine Chemical Properties
Melting point ≥300 °C(lit.)
density 1.483 (estimate)
refractive index 1.5605 (estimate)
storage temp. 2-8°C
solubility Practically insoluble in water and in ethanol (96%). It dissolves in dilute solutions of alkali hydroxides.
form lyophilized powder
pkapKa 8.22 (Uncertain)
Boiling point 555.4±42.0 °C(Predicted)
color Yellow to green
Water Solubility soluble
Merck 14,9337
BRN 157765
Stability:Stable for 1 year from date of purchase as supplied. Solutions in DMF may be stored at -20°C for up to 1 month.
CAS DataBase Reference154-42-7(CAS DataBase Reference)
EPA Substance Registry SystemThioguanine (154-42-7)
Safety Information
Hazard Codes T,Xi
Risk Statements 25-23/24/25
Safety Statements 28-36/37/39-45-28A
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS UP0740000
13
Hazard Note Irritant
HazardClass 6.1
PackingGroup III
HS Code 29335990
Hazardous Substances Data154-42-7(Hazardous Substances Data)
ToxicityLD50 oral in mouse: 160mg/kg
MSDS Information
ProviderLanguage
6-Thioguanine English
SigmaAldrich English
ACROS English
ALFA English
Thioguanine Usage And Synthesis
Description

Thioguanine is used to treat acute myeloid leukemia (AML; a type of cancer that begins in the white blood cells). Thioguanine is in a class of medications known as purine analogs. It works by slowing or stopping the growth of cancer cells in your body.

Uses

Thioguanine is an antineoplastic anti-metabolite used in the treatment of several forms of leukemia including acute nonlymphocytic leukemia. Anti-metabolites masquerade as purine or pyrimidine - which become the building blocks of DNA. They prevent these substances becoming incorporated in to DNA during the "S" phase (of the cell cycle), stopping normal development and division.

Side effects

Nausea, vomiting, loss of appetite, and mouth sores may occur. Tell your doctor right away if you have any serious side effects, including: joint pain/swelling, black stools, vomit that looks like coffee grounds, symptoms of liver disease (such as nausea/vomiting that doesn't stop, stomach/abdominal pain, yellowing eyes/skin, dark urine). This medication may decrease bone marrow function, an effect that may lead to a low number of blood cells such as red cells, white cells, and platelets. This effect can cause anemia, decrease your body's ability to fight an infection, or cause easy bruising/bleeding.

Tag:Thioguanine(154-42-7) Related Product Information
Ancitabine 6-Methylthioguanine 6-Thioguanosine hydrate 1,9-DIHYDRO-6H-PURINE-6-THIONE 6-N-HEPTYLMERCAPTOPURINE 2-Amino-6-mercaptopurine-13C2,15N 6,8-DIHYDROXY-2-METHYLMERCAPTOPURINE 6-(Methylthio)purine 6-thioinosine-5'-triphosphate 8-AZA-6-HYDROXY-2-MERCAPTOPURINE 1,7,8,9-tetrahydro-8-thioxo-6H-purin-6-one 6-METHYLMERCAPTOPURINE RIBOSIDE 2-MERCAPTOPURINE 6-METHYL-D3-MERCAPTOPURINE 2,6-Dithiopurine 1H-Imidazole-4-carboxylic acid 6-thioinosine 5'-monophosphate Thioguanine deoxyriboside,β-Thioguanine deoxyriboside