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| Diethyl cyanomethylphosphonate Basic information |
| Diethyl cyanomethylphosphonate Chemical Properties |
Boiling point | 101-102 °C0.4 mm Hg(lit.) | density | 1.095 g/mL at 25 °C(lit.) | refractive index | n20/D 1.434(lit.) | Fp | >230 °F | storage temp. | Inert atmosphere,2-8°C | solubility | Chloroform (Soluble), Methanol (Slightly) | form | Liquid | color | Clear colorless to light yellow | Specific Gravity | 1.1261.095 | Water Solubility | Miscible with water, chloroform, terahydrofuran, ethyl acetate and methylene chloride. | BRN | 1772981 | InChI | InChI=1S/C6H12NO3P/c1-3-9-11(8,6-5-7)10-4-2/h3-4,6H2,1-2H3 | InChIKey | KWMBADTWRIGGGG-UHFFFAOYSA-N | SMILES | P(CC#N)(=O)(OCC)OCC | CAS DataBase Reference | 2537-48-6(CAS DataBase Reference) | NIST Chemistry Reference | Diethyl cyanomethylphosphonate(2537-48-6) |
| Diethyl cyanomethylphosphonate Usage And Synthesis |
Chemical Properties | clear colorless to light yellow liquid | Uses | Wittig reagent. | Uses | Diethyl cyanomethyl phosphonate is used as an intermediate in Horner-Emmons reaction for the synthesis of substituted nitriles and their amide and heterocyclic derivatives. It is known as a modified Wittig reagent used in the preparation of alpha, beta-unsaturated nitriles from ketones or aldehydes like 3-hydroxy-3-methylbutanal. It reacts with epoxides and nitrones to prepare cyano-substituted cyclopropanes and aziridines respectively. It is actively involved in the synthesis of alpha-arylated alkanenitriles via reaction with aryl iodides in presence of CuI. | Biological Functions |
Diethyl cyanomethylphosphonate can be used to inhibit and/0r prevent the growth of undesirable algae, bacteria, fungi, yeast, and other microorganisms.
| General Description | Diethyl cyanomethylphosphonate is a useful chemical and medical intermediate, which can be used as raw material to synthesize nitrogen-haloamine precursor AEP-ADCT containing triazine-phosphate group |
| Diethyl cyanomethylphosphonate Preparation Products And Raw materials |
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