- 2,6-Dichloropurine
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- $0.00 / 1kg
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2024-05-30
- CAS:5451-40-1
- Min. Order: 0.10000000149011612kg
- Purity: 99
- Supply Ability: 20tons
- 2,6-Dichloropurine
-
- $455.00 / 10kg
-
2024-05-30
- CAS:5451-40-1
- Min. Order: 10kg
- Purity: 99%
- Supply Ability: 100Tons
- 2,6-Dichloropurine
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- $1.00 / 1KG
-
2024-04-20
- CAS:5451-40-1
- Min. Order: 1KG
- Purity: 99.91%
- Supply Ability: 200000
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| | 2,6-Dichloropurine Basic information |
| Product Name: | 2,6-Dichloropurine | | Synonyms: | 2,6-DICHLOROPURINE;2,6-Dichloropurine.97%;1H-Purine, 2,6-dichloro-;Dichloropurine;Cefepime Intermediate;9H-Purine, 2,6-dichloro-;6-Dichloropurine;NSC 18395 | | CAS: | 5451-40-1 | | MF: | C5H2Cl2N4 | | MW: | 189 | | EINECS: | 226-681-6 | | Product Categories: | Building Blocks;Chemical Synthesis;Halogenated Heterocycles;Heterocyclic Building Blocks;Intermediates & Fine Chemicals;Pharmaceuticals;Nucleotides;Fused Ring Systems;Building Blocks;Halogenated Heterocycles;Heterocyclic Building Blocks;PurinesHeterocyclic Building Blocks;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Bases & Related Reagents;Pyridines, Pyrimidines, Purines and Pteredines;Halides;Purine;Nucleotides and Nucleosides;Purines;FINE Chemical & INTERMEDIATES;Starting Raw Materials & Intermediates;Heterocycles;5451-40-1 | | Mol File: | 5451-40-1.mol |  |
| | 2,6-Dichloropurine Chemical Properties |
| Melting point | 185-195 °C (dec.) (lit.) | | Boiling point | 310.62°C (rough estimate) | | density | 1.7265 (rough estimate) | | refractive index | 1.6300 (estimate) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | soluble | | pka | 5.22±0.20(Predicted) | | form | Crystalline Powder | | color | White to yellow | | Water Solubility | soluble | | BRN | 9354 | | InChIKey | RMFWVOLULURGJI-UHFFFAOYSA-N | | CAS DataBase Reference | 5451-40-1(CAS DataBase Reference) |
| | 2,6-Dichloropurine Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powder | | Uses | 2,6-Dichloropurine is used in the synthesis of 2,6-diamino-substituted purine derivatives as potential cardiomyogenesis inducing agents. | | Uses | Suzuki-Miyaura cross-coupling between halopurines and arylboronic acids in water-acetonitrile.1 | | Synthesis Reference(s) | Journal of the American Chemical Society, 80, p. 404, 1958 DOI: 10.1021/ja01535a040 | | Purification Methods | It can be recrystallised from 150 parts of boiling H2O and dried at 100o to constant weight. It is soluble in EtOAc. The HgCl2 salt separates from EtOH solution. UV: max 275nm ( 8.9K) at pH 1; and 280nm ( 8.5K) at pH 11 [Elion & Hitchings J Am Chem Soc 78 3508 1956, Schaeffer & Thomas J Am Chem Soc 80 3738 1958, Beaman & Robins J Appl Chem (London) 12 432 1962, Montgomery J Am Chem Soc 78 1928 1956]. [Beilstein 26 III/IV 1747.] |
| | 2,6-Dichloropurine Preparation Products And Raw materials |
| Raw materials | HYPOXANTHINE-1-OXIDE-->ADENINE N(1)-OXIDE MONOHYDRATE, 98-->1,5-Dihydropyrrolo[3,2-a]pyrimidine-2,4-dion-->Isoamyl nitrite-->Xanthine-->6-Chloroguanine-->Guanine | | Preparation Products | 2,6-Dichloro-7-methylpurine-->Cladribine-->7H-Purine, 2,6-dichloro-7-(1-methylethyl)--->2,6-dichloro-9-(1-methylethyl)-9H-purine-->9H-Purine, 2,6-dichloro-9-propyl- |
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