- 2,2-Dimethoxyethylamine
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- $0.00 / 200KG
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2024-05-31
- CAS:22483-09-6
- Min. Order: 1KG
- Purity: ≥99%
- Supply Ability: 1000mt/year
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| Aminoacetaldehyde dimethyl acetal Basic information |
| Aminoacetaldehyde dimethyl acetal Chemical Properties |
Hazard Codes | C,F,Xi | Risk Statements | 10-34-36/37/38 | Safety Statements | 26-36/37/39-45-16-36 | RIDADR | UN 1993 3/PG 3 | WGK Germany | 2 | Hazard Note | Flammable/Corrosive | TSCA | Yes | HazardClass | 3 | PackingGroup | III | HS Code | 29225000 |
| Aminoacetaldehyde dimethyl acetal Usage And Synthesis |
Description | Aminoacetaldehyde dimethyl acetal, also known as 2,2-dimethoxy-ethylamine, is a critical intermediate in the synthesis of ivabradine hydrochloride, proline analogs, praziquantel, and other raw materials. The existing process for producing aminoacetal dimethyl acetate uses vinyl acetate as the starting material, and the target product is synthesized through bromination, Gabriel synthesis, and hydrazinolysis.
| Chemical Properties | clear colorless to pale yellow liquid | Uses | Amino acetaldehyde dimethyl was used in preparation of chitosan- dendrimer hybrids having various functional groups such as carboxyl, ester and poly(ethylene glycol). It was used in an synthesis of a bicyclic proline analog from L-ascorbic acid and in 3-component reaction catalyzed by MgClO4 leading to α-aminophosphonates. | General Description | Aminoacetaldehyde dimethyl acetal reacts with sulfone, followed by hydrolysis and reductive amination by adding desired piperazine derivative to yield piperazine derivatives of 2-furanyl[1,2,4]triazolo[1,5-a][1,3,5]triazine. | Purification Methods | Dry the acetal over KOH pellets and distil it through a 30cm vacuum jacketed Vigreux column (p 11). [Lawson J Am Chem Soc 75 3398 1953, Erickson et al. J Am Chem Soc 77 6640 1955, Beilstein 4 IV 1918.] |
| Aminoacetaldehyde dimethyl acetal Preparation Products And Raw materials |
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