DENDROTOXIN-K

DENDROTOXIN-K Suppliers list

Company Name:	Sigma-Aldrich
Tel:	021-61415566 800-8193336
Email:	orderCN@merckgroup.com
Products Intro:	Product Name:Dendrotoxin-K Purity:>= 98 % HPLC, lyophilized powder Package:1vial Remarks:D4813

Company Name:	Beijing Bai Ao Si Biotechnology Co., Ltd.
Tel:	010-60291560
Email:	yangmei@bioneeds.net
Products Intro:	Product Name:Dendrotoxin-K

Company Name:	Beijing Bolide Biotechnology Co., Ltd.
Tel:	010-51653916
Email:	1985563437@qq.com
Products Intro:	Product Name:Dendrotoxin-K

Company Name:	Beijing Sizhengbai Biotechnology Co., Ltd.
Tel:	400-7060-959
Email:	marketing@4abio.com
Products Intro:	Product Name:Dendrotoxin-K

Company Name:	Shanghai Silk Dragon Biological Technology Co., Ltd.
Tel:	021-64221773
Email:
Products Intro:	Product Name:Dendrotoxin-K

DENDROTOXIN-K Basic information

Product Name:	DENDROTOXIN-K
Synonyms:	DENDROTOXIN-K
CAS:
MF:
MW:	0
EINECS:
Product Categories:	Monovalent Ion Channels;Potassium Channel Modulators;Voltage-gated Ion Channels
Mol File:	Mol File

DENDROTOXIN-K Chemical Properties

storage temp.	−20°C
form	lyophilized powder

Safety Information

RIDADR	UN 3462 6.1/PG 3
WGK Germany	3

MSDS Information

Provider	Language
SigmaAldrich	English

DENDROTOXIN-K Usage And Synthesis

Uses	Dendrotoxin-K is suitable for use as a potassium voltage-gated channel subfamily A member 1 (Kv1.1) channel blocker in axon and human embryonic kidney (HEK293) cells. It has also been used as a selective blocker of Kv channels in mice.
Biochem/physiol Actions	Dendrotoxin-K (DTXk) is isolated from mamba snake Dendroaspis polylepis and interacts with the β-turn region in the N-terminal sequence of the potassium channel. It inhibits tumor progression in gefitinib-resistant non-small cell lung cancer cells. DTXk induces neuronal damage in the hippocampus via N-methyl-d-aspartate (NMDA) and non-NMDA receptors.

DENDROTOXIN-K Preparation Products And Raw materials

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