ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >fatty acid >1-Adamantanecarboxylic acid

1-Adamantanecarboxylic acid

1-Adamantanecarboxylic acid Suppliers list
Company Name: Huzhou Chenxi Environmental Protection Technology Co. , Ltd.
Tel: +8616762203950
Email: 1034385273@qq.com
Products Intro: Product Name:1-Adamantane Carboxylic Acid
CAS:828-51-3
Purity:99% Package:1KG;10KG;25KG
Company Name: Henan Allgreen Chemical Co.,LTD
Tel: +86-37155567971 +86-13633837469
Email: info@allgreenchem.com
Products Intro: Product Name:1-Adamantanecarboxylic acid
CAS:828-51-3
Package:1kg, 5kg, 25kg, 50kg, 200kg
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +86 13288715578 +8613288715578
Email: sales@hbmojin.com
Products Intro: Product Name:1-Adamantanecarboxylic acid
CAS:828-51-3
Purity:99% Package:25KG
Company Name: Hebei Chuanghai Biotechnology Co,.LTD
Tel: +86-13131129325
Email: sales1@chuanghaibio.com
Products Intro: Product Name:1-Adamantanecarboxylic acid
CAS:828-51-3
Purity:99% Package:1KG;5.00;USD|10KG;3.00;USD|50KG;2.00;USD
Company Name: Hebei Zhuanglai Chemical Trading Co.,Ltd
Tel: +8613343047651
Email: admin@zlchemi.com
Products Intro: Product Name:1-Adamantanecarboxylic acid
CAS:828-51-3
Purity:99 Package:1kg;100USD

1-Adamantanecarboxylic acid manufacturers

1-Adamantanecarboxylic acid Basic information
Product Name:1-Adamantanecarboxylic acid
Synonyms:1-ADMANTANE CARBOXYLIC ACID;1-Adamantane-1-carboxylic acid;1-Adamantanecarboxylic acid ,99%;3-adamantanecarboxylicacid;ricyclo[3.3.1.13,7]decane-1-carboxylic acid;Tricyclo[3.3.1.13,7]-decane-1-carboxylic acid;Tricyclo[3,3,1,1]3,7 decanecarbonoic acid;1-Adamantan Carboxylic Acid
CAS:828-51-3
MF:C11H16O2
MW:180.24
EINECS:212-584-6
Product Categories:C11 to C12;Carbonyl Compounds;Carboxylic Acids;Organic acids;Adamantanes
Mol File:828-51-3.mol
1-Adamantanecarboxylic acid Structure
1-Adamantanecarboxylic acid Chemical Properties
Melting point 172-174 °C (lit.)
Boiling point 253.08°C (rough estimate)
density 0.9976 (rough estimate)
refractive index 1.4910 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform, Methanol (Slightly)
form Crystalline Powder
pka4.86±0.20(Predicted)
color White to off-white
Water Solubility Insoluble in water. Solubility in methanol gives very faint turbidity. Soluble in ethanol, chloroform, and dichloromethane.
BRN 1910637
InChIInChI=1S/C11H16O2/c12-10(13)11-4-7-1-8(5-11)3-9(2-7)6-11/h7-9H,1-6H2,(H,12,13)
InChIKeyJIMXXGFJRDUSRO-UHFFFAOYSA-N
SMILESC12(C(O)=O)CC3CC(CC(C3)C1)C2
CAS DataBase Reference828-51-3(CAS DataBase Reference)
NIST Chemistry ReferenceAdamantane-1-carboxylic acid(828-51-3)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 22-24/25-36-26
WGK Germany 3
RTECS AU4452200
Hazard Note Irritant
HS Code 29162000
MSDS Information
ProviderLanguage
Tricyclo[3.3.1.1(3,7)]decan-1-Carboxylic acid English
SigmaAldrich English
ACROS English
ALFA English
1-Adamantanecarboxylic acid Usage And Synthesis
Chemical Propertieswhite to off-white crystalline powder
Uses1-Adamantanecarboxylic acid can be used as:
  • A stabilizer in the synthesis of monodisperse, highly crystalline CoPt3?nanoparticles and porous platinum nanoparticles.
  • An additive in polycondensation reactions to yield conjugated polymers as possible optoelectronic materials.
  • An additive in the allylic substitution reaction, which is catalyzed by palladium in an aqueous medium.

UsesIt can be used as a stabilizer in the synthesis of monodisperse, highly crystalline CoPt3 nanoparticles1 and porous platinum nanoparticles. It is a potent and reversible CerK inhibitor.
UsesAdamantoic Acid is an inhibitor of chorismate mutase activity and hydroxyphenylpyruvate synthase. It inhibits TTR conformational changes facilitating amyloid fibril formation.
Synthesis Reference(s)Synthetic Communications, 18, p. 545, 1988 DOI: 10.1080/00397918808060749
Biochem/physiol Actions1-Adamantanecarboxylic acid undergoes complexation reactions with cyclohexaamylose. It is an inhibitor of phenyl ester hydrolysis of cycloheptaamylose.
Purification MethodsPossible impurities are trimethylacetic acid and C9 and C13 acids. Dissolve 15g of the acid in CCl4 (300mL) and shake with 110mL of 15N aqueous NH3 whereby the ammonium salt separates and is collected. Acid impurities form soluble ammonium salts. The salt is washed with cold Me2CO (20mL) and suspended in H2O (250mL). This is treated with 12N HCl and extracted with CHCl3 (100mL). The dried (Na2SO4) extract was evaporated and the residue was recrystallised from a mixture of MeOH (30mL) and H2O (ca 10mL) to give the pure acid (10-11g). [Koch & Haaf Org Synth Coll Vol V 20 1973.] It was also recrystallised from absolute EtOH and dried under vacuum at 100o. Alternatively, the acid (5g) is refluxed for 2hours with 15mL of MeOH and 2mL of 98% H2SO4 (cool when mixing this solution). Pour into 10 volumes of H2O and extract with the minimum volume of CHCl3 to give clear separation of phases. The extract is washed with H2O, dried (CaCl2) and distilled. The methyl ester is collected at 77-79o/1mm, m 38-39o. The ester is hydrolysed with the calculated amount of N KOH and refluxed until clear. Acidification with HCl provides the pure acid with 90% recovery. The amide crystallises from cyclohexane, m 189o. [Stetter et al. Chem Ber 92 1629 1959.] [Beilstein 9 IV 253.]
Tag:1-Adamantanecarboxylic acid(828-51-3) Related Product Information
Citric acid 1-Adamantanol Adamantane Glycine Amantadine Ethyl 2-(Chlorosulfonyl)acetate Altrenogest Folic acid Ascoric Acid 1-ADAMANTANECARBOXYLIC ACID ETHYL ESTER AMANTANIUM BROMIDE 4-KETO-1-ADAMANTANECARBOXYLIC ACID,4-OXO-1-ADAMANTANECARBOXYLIC ACID Bolmantalate 3-(ACETYLAMINO)-1-ADAMANTANECARBOXYLIC ACID,1-ACETYLAMINO-3-ADAMANTANECARBOXYLIC ACID 3-BROMO-1-ADAMANTANECARBOXYLIC ACID 3-Hydroxy-1-AdaMantane Carboxylic Acid 1-ADAMANTANECARBOXYLIC ACID CHLORIDE,1-ADAMANTANECARBOXYLIC ACID CHLOROANHYDRIDE 3-(4-NITROPHENYL)-1-ADAMANTANECARBOXYLIC ACID