4-Methylphenyl isothiocyanate manufacturers
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| | 4-Methylphenyl isothiocyanate Basic information |
| | 4-Methylphenyl isothiocyanate Chemical Properties |
| Melting point | 25-26 °C (lit.) | | Boiling point | 237 °C (lit.)
62 °C/0.3 mmHg (lit.) | | density | 1.1442 (rough estimate) | | refractive index | n20/D 1.6345(lit.) | | Fp | 107 °C | | storage temp. | Store below +30°C. | | form | powder to lump | | color | White to Light yellow | | Water Solubility | MAY DECOMPOSE | | Sensitive | Moisture Sensitive | | BRN | 386032 | | InChIKey | ABQKHKWXTUVKGF-UHFFFAOYSA-N | | CAS DataBase Reference | 622-59-3(CAS DataBase Reference) | | NIST Chemistry Reference | Benzene, 1-isothiocyanato-4-methyl-(622-59-3) |
| | 4-Methylphenyl isothiocyanate Usage And Synthesis |
| Chemical Properties | clear light yellow liquid after melting | | Uses | p-Tolyl isothiocyanate has been used:
- in the preparation of 6-[1-amino-3-(p-tolyl)-thiourea]-2-ethylbenzo[de]isoquinoline-1,3-dione
- as capping agent to cap the N-terminal ends of polypeptides
| | Uses | p-Tolyl isothiocyanate has been used in the preparation of 6-[1-amino-3-(p-tolyl)-thiourea]-2-ethylbenzo[de]isoquinoline-1,3-dione. It is used as capping agent to cap the N-terminal ends of polypeptide. It is also used as pharmaceutical intermediate. | | General Description | p-Tolyl isothiocyanate reacts with 6-hydroxy-2,4,5-triaminopyrimidine or with 4,5,6-triaminopyrimidine in DMF and triethylamine to yield 2,4-diamino-5-(p-tolylthioureido)aminopyrimidin-6-one and 4,6-diamino-5-(tolylthioureido)aminopyrimidine, respectively. |
| | 4-Methylphenyl isothiocyanate Preparation Products And Raw materials |
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