| Company Name: |
Dy - Mach Pharma
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| Tel: |
+91-2265018321 +91-2226833227 |
| Email: |
info@dymachpharma.com |
| Products Intro: |
Product Name:Sulfaethidole
CAS:94-19-9
Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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| Company Name: |
J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:4-Amino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzene sulfonamide
CAS:94-19-9
Package:500mg
|
| Company Name: |
Wuhan Chemwish Technology Co., Ltd
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| Tel: |
86-027-67849912 |
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sales@chemwish.com |
| Products Intro: |
Product Name:4-AMino-N-(5-ethyl-[1,3,4]thiadiazol-2-yl)-benzenesulfonaMide
CAS:94-19-9
Purity:98% Package:1g;5g;25g;50g;100g;500g
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| | 4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Basic information |
| | 4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Chemical Properties |
| Melting point | 185.5-186.0° | | density | 1.3410 (rough estimate) | | refractive index | 1.6440 (estimate) | | pka | pKa 5.36(H2O
t = 37) (Uncertain) | | Water Solubility | 215mg/L(20 ºC) |
| Hazard Codes | Xi | | HazardClass | IRRITANT | | Toxicity | LD50 intraperitoneal in mouse: 1459mg/kg |
| | 4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Usage And Synthesis |
| Originator | Sul-Spansion,SKF,US,1956 | | Definition | ChEBI: 4-amino-N-(5-ethyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide is a member of benzenes and a sulfonamide. | | Manufacturing Process | 0.163 mol of 2-amino-5-ethyl-1,3,4-thiadiazole was covered with 43 parts of
anhydrous pyridine. To the mixture was added 50 parts (0.214 mol) of pacetylaminobenzenesulfonyl
chloride with vigorous shaking at 50°C to 60°C.
The reaction mixture was then heated to 125°C. When the mixture had cooled
somewhat it was placed in a Claisen flask and 27.6 parts (0.69 mol) of
sodium hydroxide dissolved in 110 parts of water was added through a
dropping funnel while distilling off a mixture of pyridine and water. The
distillation was stopped when the temperature reached 100°C and the residual
liquor in the flask heated at 95°C for 30 minutes.The reaction mixture was then poured into 1,650 parts of hot water, the pH
adjusted to 8 to 9, decolorizing charcoal was added and the whole was heated
on the steam for 15 minutes. The charcoal was filtered off and the hot filtrate
neutralized and cooled. The 2-(sulfanilamido)-5-ethyl-1,3,4-thiadiazole was
purified by repeated crystallization from boiling water. | | Therapeutic Function | Antibacterial |
| | 4-AMINO-N-(5-ETHYL-[1,3,4]THIADIAZOL-2-YL)-BENZENESULFONAMIDE Preparation Products And Raw materials |
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