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| | 2-Chloro-1,3-dimethylimidazolidinium chloride Chemical Properties |
| Melting point | 133-140 °C (lit.) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | solubility | Chloroform, Methanol, Water | | form | Powder or Crystalline Powder | | color | White to off-white | | Merck | 13,3424 | | Stability: | Hygroscopic | | InChIKey | AEBBXVHGVADBHA-UHFFFAOYSA-M | | CAS DataBase Reference | 37091-73-9(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | RIDADR | 1593 | | WGK Germany | 3 | | F | 3-10-21 | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 29332900 |
| | 2-Chloro-1,3-dimethylimidazolidinium chloride Usage And Synthesis |
| Description | 2-Chloro-1,3-dimethylimidazolidinium chloride has various applications including being used as activating agent in total synthesis of macroviracin A, cycloviracin B1 and cyclic silanes; used as reagent for synthesis of tagged glucose as an intermediate in the synthesis of branched oligosaccharides; used as fluorescent chemosensors; 1,2-Diamines as inhibitors of co-activator associated arginine methyltransferase 1; used as allosteric glucokinase activators; as reactant for synthesis of organic azides from primary amines and for aza-Henry reactions1. It can act as a powerful dehydrating agent, replacing DCC under nearly neutral conditions, and has application for the construction of heterocycles2. Moreover, it can be used for one-pot synthesis of 2-aminobenzimidazoles3. It is also applicable to chlorination, oxidation, reduction, and rearrangement under nearly neutral conditions4.
| | Sources |
- https://www.sigmaaldrich.com/catalog/product/aldrich/529249?lang=en®ion=US
- https://pubs.acs.org/doi/abs/10.1021/jo990210y
- www.sciencedirect.com/science/article/pii/S004040391001395X
- J. Org. Chem., 1999, 64 (16), pp 5832–5835
| | Chemical Properties | Brown Solid | | Uses | Reagent for synthesis of:
Tagged glucose as an intermediate in the synthesis of branched oligosaccharides
Fluorescent chemosensors
1,2-Diamines as inhibitors of co-activator associated arginine methyltransferase 1
Allosteric glucokinase activators
Reactant for synthesis of:
Organic azides from primary amines
Reagent for aza-Henry reactions | | Uses | Used in the one-pot synthesis of 2-aminobenzimidazoles. |
| | 2-Chloro-1,3-dimethylimidazolidinium chloride Preparation Products And Raw materials |
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