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| | 1,7-Bis-boc-1,4,7-triazaheptane Basic information |
| Product Name: | 1,7-Bis-boc-1,4,7-triazaheptane | | Synonyms: | 1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE;N,N-Bis[2-(tert-butoxycarbonylaMino)ethyl]aMine;dicarbamate;Di-tert-butyl (azanediylbis(ethane-2,1-diyl);bis(2-tert-butyloxycarbonylaminoethyl)amine;10-Oxa-2,5,8-triazadodecanoic acid, 11,11-dimethyl-9-oxo-, 1,1-dimethylethyl ester;tert-butyl N-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]ethyl]carbamate;Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbaMate | | CAS: | 117499-16-8 | | MF: | C14H29N3O4 | | MW: | 303.4 | | EINECS: | | | Product Categories: | Miscellaneous Reagents | | Mol File: | 117499-16-8.mol |  |
| | 1,7-Bis-boc-1,4,7-triazaheptane Chemical Properties |
| Melting point | 68-70°C | | Boiling point | 440.5±30.0 °C(Predicted) | | density | 1.035±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) | | pka | 12.28±0.46(Predicted) | | form | Solid | | color | White to Off-White |
| Safety Statements | 24/25 | | HS Code | 29225090 |
| | 1,7-Bis-boc-1,4,7-triazaheptane Usage And Synthesis |
| Description | 1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE contains two Boc protecting groups which can be removed under acidic conditions. The remaining free amines can further react with carbonyl moieties. | | Chemical Properties | 1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE is white powder | | Uses | 1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE is used in the preparation of bifunctional chelators that have been then applied to the synthesis of monoclonal antibody conjugates for tumor targeting. | | in vitro | 1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins |
| | 1,7-Bis-boc-1,4,7-triazaheptane Preparation Products And Raw materials |
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