| Company Name: |
Block Chemical Technology (Shanghai) Co., LTD
|
| Tel: |
021-20432219 13918097649 |
| Email: |
li_jinfei@acblock-lab.com |
| Products Intro: |
Product Name:1-(3-methylphenoxy)-3-[(propan-2-yl)amino]propan-2-ol hydrochloride
CAS:306-11-6
Purity:95% by NMR Package:1G,5G Remarks:R&D in stock EN
|
| Company Name: |
CHEMICAL LAND21
|
| Tel: |
82- 2 -783 - 8063 |
| Email: |
sales21@chemicalland21.com |
| Products Intro: |
|
|
| | [2-hydroxy-3-(m-tolyloxy)propyl]isopropylammonium chloride Basic information |
| Product Name: | [2-hydroxy-3-(m-tolyloxy)propyl]isopropylammonium chloride | | Synonyms: | [2-hydroxy-3-(m-tolyloxy)propyl]isopropylammonium chloride;1-(3-methylphenoxy)-3-(propan-2-ylamino)propan-2-ol hydrochloride;1-(isopropylamino)-3-(3-methylphenoxy)propan-2-ol hydrochloride;2-Hydroxy-3-(3-methylphenoxy)propyl](propan-2-yl)amine Hydrochloride | | CAS: | 306-11-6 | | MF: | C13H22ClNO2 | | MW: | 259.77228 | | EINECS: | 206-177-2 | | Product Categories: | | | Mol File: | 306-11-6.mol | ![[2-hydroxy-3-(m-tolyloxy)propyl]isopropylammonium chloride Structure](CAS/GIF/306-11-6.gif) |
| | [2-hydroxy-3-(m-tolyloxy)propyl]isopropylammonium chloride Chemical Properties |
| | [2-hydroxy-3-(m-tolyloxy)propyl]isopropylammonium chloride Usage And Synthesis |
| Originator | Doberol,Boehringer, Ing. | | Manufacturing Process | 59 g (1 mol) of isopropylamine in 60 ml of water are added to a solution of 82
g (0.5 mol) of 3-(3'-methylphenoxy)propylene oxide (prepared from 3-methyl phenol and epichlorohydrin) in 400 ml of ethanol. After the exothermic
reaction has subsided, the mixture is heated for 2 hours at 60°C. After
distillation of the volatile components, the free base remains as a solid
residue. It is dissolved in hydrochloric acid the acid solution is extracted with
ether and then made alkaline with caustic soda solution. The base crystallizes
out and is dried over P2O5; 101.9 g (91.3% of theory) of 1-(isopropylamino)-
3-(m-tolyloxy)-2-propanol being obtained; it is recrystallized from ethyl
acetate/petroleum ether, and then has MP: 75-76°C. Upon addition of ethereal
hydrogen chloride to an alcoholic solution of the base, the hydrochloride
precipitates, and after recrystallization from alcohol/ether, has MP: 120-
121°C. | | Therapeutic Function | Beta-adrenergic blocker |
| | [2-hydroxy-3-(m-tolyloxy)propyl]isopropylammonium chloride Preparation Products And Raw materials |
|