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| | 3-METHYLTHIOPHENE-2-CARBONITRILE Basic information |
| | 3-METHYLTHIOPHENE-2-CARBONITRILE Chemical Properties |
| Boiling point | 91-93°C 12mm | | refractive index | 1.5530 | | Fp | 91-93°C/12mm | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | BRN | 5495606 | | CAS DataBase Reference | 55406-13-8(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 20/21/22 | | Safety Statements | 36/37/39 | | RIDADR | 3276 | | Hazard Note | Irritant | | HazardClass | 6.1 | | PackingGroup | III | | HS Code | 2934999090 |
| Provider | Language |
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ALFA
| English |
| | 3-METHYLTHIOPHENE-2-CARBONITRILE Usage And Synthesis |
| Preparation | 3-Methylthiophene-2-carbonitrile synthesis: 3-Methyl-2-thiophenecarboxamide (18.6 g, 0.13 mol) was mixed with an excess of POCl3, and the mixture heated at reflux temperature for 2 h. The excess POCl3 was removed under vacuum and the residue dissolved in 500 mL of 1,2-dichloroethane, washed (carefully!) with water, then brine, and the solvent removed to give 23 g of crude 3-methyl-2-thiophenecarbonitrile. This material was passed through a plug of silica gel with CH2Cl2 and the solvent evaporated to give 16.2 g (100%) of as a light tan oil: 1H NMR (CDCl3) d 7.4 (d, J=4.8 Hz, 1H), 6.9 (d, J=5.4 Hz, 1H), 2.4 ppm (s, 3H); 97% pure by HPLC area %. |
| | 3-METHYLTHIOPHENE-2-CARBONITRILE Preparation Products And Raw materials |
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