|
|
| | Tylophorinine Basic information |
| Product Name: | Tylophorinine | | Synonyms: | Tylophorinine;Dibenzo[f,h]pyrrolo[1,2-b]isoquinolin-14-ol, 9,11,12,13,13a,14-hexahydro-3,6,7-trimethoxy-, (13aR,14S)-rel- | | CAS: | 6799-27-5 | | MF: | C23H25NO4 | | MW: | 379.45 | | EINECS: | | | Product Categories: | | | Mol File: | 6799-27-5.mol |  |
| | Tylophorinine Chemical Properties |
| Melting point | 248-9°C | | Boiling point | 588.5±50.0 °C(Predicted) | | density | 1.31±0.1 g/cm3(Predicted) | | pka | 13.48±0.20(Predicted) |
| | Tylophorinine Usage And Synthesis |
| Description | An alkaloid of Tylophora asthmatica, the base crystallizes as the hemihydrate,
m.p. 232-3°C (dec.) and has[α]27D - 14.2° (c 1.76, CHCI3). The ultraviolet
spectrum in MeOH has absorption maxima at 258, 287 and 340 Mu. The salts
crystallize well, e.g. the hydrochloride, m.p. 257°C (dec.); nitrate, m.p. 240-
2°C; methiodide, m.p. 243-5°C (dec.) and the O-acetate, m.p. 222-3°C. | | References | Hooper., Pharm. J., 21,6 (1891)
Chopra et al., Arch. Pharm., 275,236 (1937)
Govindachari, Pai, Nagarajan.,J. Chem. Soc., 2801 (1954)
Govindachari et al., Tetrahedron, 14,288 (1961) |
| | Tylophorinine Preparation Products And Raw materials |
|