ChemicalBook > Product Catalog >Biochemical Engineering >Plant extracts >6-Hydroxypurine

6-Hydroxypurine

6-Hydroxypurine Suppliers list
Company Name: Hebei Mojin Biotechnology Co., Ltd
Tel: +86 13288715578 +8613288715578
Email: sales@hbmojin.com
Products Intro: Product Name:6-Hydroxypurine
CAS:68-94-0
Purity:99% Package:25KG
Company Name: airuikechemical co., ltd.
Tel: +undefined86-15315557071
Email: sales02@sdzhonghuimaterial.com
Products Intro: Product Name:6-Hydroxypurine
CAS:68-94-0
Purity:99.9% Package:1Kg;0.00;USD|5Kg;0.00;USD|25Kg;0.00;USD
Company Name: Shaanxi TNJONE Pharmaceutical Co., Ltd
Tel: +8618092446649
Email: sarah@tnjone.com
Products Intro: Product Name:6-Hydroxypurine;Hypoxanthine
CAS:68-94-0
Purity:99% Package:1kg
Company Name: Hebei Zhuanglai Chemical Trading Co.,Ltd
Tel: +8613343047651
Email: admin@zlchemi.com
Products Intro: Product Name:Hypoxanthine
CAS:68-94-0
Purity:99% Package:1kg;120USD
Company Name: HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Tel: +86-15350851019 +86-15383190639
Email: admin@86-ss.com
Products Intro: Product Name:6-Hydroxypurine
CAS:68-94-0
Purity:99% Package:1kg;999USD|10kg;950USD|50kg;800USD

6-Hydroxypurine manufacturers

  • Hypoxanthine
  • Hypoxanthine pictures
  • $0.00 / 5Kg
  • 2024-10-31
  • CAS:68-94-0
  • Min. Order: 1Kg
  • Purity: 98%
  • Supply Ability: 20Ton
  • 6-Hydroxypurine
  • 6-Hydroxypurine pictures
  • $999.00/ kg
  • 2024-10-31
  • CAS:68-94-0
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 5000
  • Hypoxanthine
  • Hypoxanthine  pictures
  • $120.00 / 1kg
  • 2024-10-31
  • CAS:68-94-0
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 10ton
6-Hydroxypurine Basic information
Product Name:6-Hydroxypurine
Synonyms:HYPOXANTHINE ANHYDROUS;Hypoxanthinee;HYPOXANTHINE(RG);6-HYDROXYPURINE(HYPOXANTHINE);purine-6(1H)-one;Hypexanthine;6-oxypurine;HYPOXANTHINE extrapure
CAS:68-94-0
MF:C5H4N4O
MW:136.11
EINECS:200-697-3
Product Categories:Purine;Chemical Amines;Azathiaprine;Mercaptopurine;Biochemistry;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Nucleic acids;Amines;Aromatics;Heterocycles;Metabolites & Impurities;PYRIMIDINE;Pharmaceutical Intermediates;Amines, Aromatics, Heterocycles, Metabolites & Impurities;bc0001;68-94-0;DDQ
Mol File:68-94-0.mol
6-Hydroxypurine Structure
6-Hydroxypurine Chemical Properties
Melting point >300 °C (lit.)
Boiling point 250.36°C (rough estimate)
density 1.4295 (rough estimate)
refractive index 1.8500 (estimate)
storage temp. 2-8°C
solubility 1 M NaOH: 25 mg/mL
form powder
pka8.7(at 25℃)
color Colorless to yellow to brown, darken on storage with no loss of purity
OdorOdorless
Water Solubility practically insoluble
Merck 14,4869
BRN 5811
InChIKeyFDGQSTZJBFJUBT-UHFFFAOYSA-N
LogP-0.910 (est)
CAS DataBase Reference68-94-0(CAS DataBase Reference)
NIST Chemistry ReferenceHypoxanthine(68-94-0)
EPA Substance Registry SystemHypoxanthine (68-94-0)
Safety Information
Hazard Codes Xn
Risk Statements 36/37/38-22-40
Safety Statements 22-24/25-37/39-26-36
WGK Germany 3
RTECS UP0791000
Hazard Note Harmful
TSCA Yes
HS Code 29335990
ToxicityLD50 intraperitoneal in mouse: 750mg/kg
MSDS Information
ProviderLanguage
6-Hydroxypurine English
SigmaAldrich English
ACROS English
ALFA English
6-Hydroxypurine Usage And Synthesis
DescriptionHypoxanthine is a naturally occurring purine derivative and intermediate in the synthesis of uric acid. It is elevated in the spinal fluid of patients with Lesch-Nyhan syndrome, a metabolic disorder whose symptoms include cerebral palsy, cognitive deficits, motor dysfunction, self-mutilation, and hyperuricemia. Injection of hypoxanthine (10 μM) increases succinate dehydrogenase and complex II activities and decreases cytochrome c oxidase activity, resulting in neuroenergetic impairment, ATP depletion, and cellular apoptosis in rat striatum. It is also used to induce hyperuricemia in mice for use in the development of hypouricemic agents.
Chemical PropertiesWhite to off-white powder
UsesHypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. The compound has been used in studies as in indicator, along with uric acid and allantoin , of in vivo free radical reactions. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies along with 8-oxoguanine nucleotides to investigate their interaction with human DNA pol ? (DNA polymerase alpha) and DNA polymerase I from Bacillus stearothermophilus. It is also used as a pharmaceutical intermediate.
UsesHypoxanthine is a nutrient additive for a variety of cell culture applications involving bacterial, parasite (Plasmodium falciparum) and animal cells. Hypoxanthine is a component of selection media used in hybridoma technologies.
UsesA naturally occurring purine derivative. Pharmaceuticals, Intermediates & Fine Chemicals
DefinitionChEBI: A purine nucleobase that consists of purine bearing an oxo substituent at position 6.
General DescriptionHypoxanthine (6-hydroxypurine), a purine derivative is a naturally occurring compound. It is the deaminated form of adenine and a breakdown product of adenosine monophosphate (AMP).
Biochem/physiol ActionsHypoxanthine?is capable of stimulating cell death. It can also induce reactive oxygen species (ROS). It results in endothelial dysfunction via apoptosis, stimulated by oxidative stress.
Safety ProfileModerately toxic by intraperitoneal route. An experimental teratogen. When heated to decomposition it emits toxic fumes of Nox
Purification MethodsCrystallise it from hot water and dry it at 105o. [Beilstein 26 II 252, 26 III/IV 2081.]
Tag:6-Hydroxypurine(68-94-0) Related Product Information
6-Mercaptopurine disulfide GUANERAN Ethanone, 1-[6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]-9H-purin-9-yl]- 8-Methyl-7H-purin-6-ol 9H-Purine, 9-β-D-arabinofuranosyl-6-[(1-methyl-4-nitro-1H-imidazol-5-yl)thio]- 1H-Imidazol-5-amine,1-methyl-4-nitro-(9CI) 4,5-Dichloroimidazole 1,7-DIHYDRO-2-METHYL-6-PURINONE Azathioprine EP Impurity E Azathioprine EP Impurity D 1-METHYL-2,4,5-TRICHLOROIMIDAZOLE 2-Chloro-1-methyl-1H-imidazole 1-Methyl-4-Chloroimidazole 4,5-DICHLORO-1-METHYLIMIDAZOLE 5-Chloro-1-methylimidazole (Z)-3-((2'-(N'-hydroxycarbaMiMidoyl)biphenyl-4-yl)Methyl)-2-oxo-2,3-dihydro-1H-benzo[d]iMidazole-4-carboxylic acid Disodium 5'-Inosinate Theophylline monohydrate