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| | Sodium prasterone sulfate Basic information |
| Product Name: | Sodium prasterone sulfate | | Synonyms: | Dehydroepiandrosterone-3-sulfate Sodium Salt
Sodium Dehydroisoandrosterone-3-sulfate;DHEA sulfate,sodiuM salt;Androst-5-en-17-one, 3-(sulfooxy)-, sodium salt, (3.beta.)-;Androst-5-en-17-one, 3.beta.-hydroxy-, hydrogen sulfate, sodium salt;sodium dehydroepiandrosterone-3-sulfate;sodium dehydroisoandrosterone-3-sulfate;SODIUM PRASTERONR SULFATE;Androst-5-en-17-one, 3-(sulfooxy)-, sodium salt, (3b)- (9CI) | | CAS: | 1099-87-2 | | MF: | C19H27NaO5S | | MW: | 390.47 | | EINECS: | 214-152-2 | | Product Categories: | Steroids.;Intermediates & Fine Chemicals;Pharmaceuticals;17-Ketosteroids;Biochemistry;Steroids;pharmaceutical intermediate and chemical research;Chemical | | Mol File: | 1099-87-2.mol |  |
| | Sodium prasterone sulfate Chemical Properties |
| Melting point | 148-149 °C (dec.)(lit.) | | refractive index | 10 ° (C=4, MeOH) | | Fp | 9℃ | | storage temp. | -20°C | | solubility | methanol: clear to hazy | | form | powder | | color | white to off-white | | Merck | 14,2871 | | InChIKey | GFJWACFSUSFUOG-QGVZUKINNA-M | | SMILES | [C@]12([H])CC[C@]3(C)C(CC[C@@]3([H])[C@]1([H])CC=C1C[C@@H](OS([O-])(=O)=O)CC[C@]21C)=O.[Na+] |&1:0,4,9,11,17,25,r| | | CAS DataBase Reference | 1099-87-2(CAS DataBase Reference) |
| Hazard Codes | F,C,T | | Risk Statements | 11-34-39/23/24/25-23/24/25 | | Safety Statements | 16-26-36/37/39-45-36/37-7 | | RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | | WGK Germany | 3 | | RTECS | BV8397400 | | Toxicity | dog,LD50,intravaginal,> 500mg/kg (500mg/kg),Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 40, Pg. 444, 1998. |
| | Sodium prasterone sulfate Usage And Synthesis |
| Description | Dehydroepiandrosterone sulfate (DHEAS) is a metabolite of dehydroepiandrosterone that is the major secretory product of adrenal glands and is the predominant circulating precursor for active steroid hormones in humans. For example, in the fetoplacental-maternal unit, DHEAS acts as the primary precursor for placental estrogen biosynthesis. A normal circulating concentration of DHEAS is ~10 μM in young adults and is dramatically increased in some adrenocortical disorders. | | Chemical Properties | White to Off-White Solid | | Uses | An active agent in the preparation of a pharmaceutical for the treatment of asthma or other respiratory diseases. | | Definition | ChEBI: An organic sodium salt that is the monosodium salt of dehydroepiandrosterone sulfate. |
| | Sodium prasterone sulfate Preparation Products And Raw materials |
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