- 5-Bromopyrimidin-2-amine
-
- $122.00 / 1KG
-
2024-01-11
- CAS:7752-82-1
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
|
| | 2-Amino-5-bromopyrimidine Basic information |
| | 2-Amino-5-bromopyrimidine Chemical Properties |
| Melting point | 241-243 °C (lit.) | | Boiling point | 340.7±34.0 °C(Predicted) | | density | 1.844±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly, Heated) | | pka | 1.93±0.10(Predicted) | | form | Crystalline Powder, Crystals or Flakes | | color | White to light beige | | Water Solubility | Insoluble | | InChIKey | UHRHPPKWXSNZLR-UHFFFAOYSA-N | | CAS DataBase Reference | 7752-82-1(CAS DataBase Reference) |
| Hazard Codes | Xn,N,Xi | | Risk Statements | 22-36-50/53 | | Safety Statements | 26-60-61 | | RIDADR | UN 3077 9/PG 3 | | WGK Germany | 3 | | Hazard Note | Harmful | | HazardClass | IRRITANT, IRRITANT-HARMFUL | | PackingGroup | III | | HS Code | 29335995 |
| | 2-Amino-5-bromopyrimidine Usage And Synthesis |
| Chemical Properties | Yellow Solid | | Uses | 2-Amino-5-bromopyrimidine was employed:
- in synthesis of pyridine, pyrimidine and pyridinone C-nucleoside phosphoramidites
- in synthesis of 2-phthalimido-5-bromopyrimidine
- as intermediate for the preparation of sulfanilamides and amino acids containing the pyrimidine ring system. The products are potential antiviral agents
| | General Description | Crystal structure of 2-amino-5-bromopyrimidine was studied. | | Synthesis | The synthesis of 2-Amino-5-bromopyrimidine is as follows:The 2-aminopyrimidine (2.5g, 26.29mmol) was dissolved in acetonitrile (25mL) was added N- bromosuccinimide (4.6g, 27.9mmol) under ice-cooling, stirred in the dark overnight at room temperature. Recovery of the solvent under reduced pressure, washed with water (100 mL) was washed, filtered off with suction, and dried in vacuo to give a white solid. Yield: 97%.
 | | storage | Store in cool, well ventilated area. Keep container tightly closed. Light sensitive. Store under argon. |
| | 2-Amino-5-bromopyrimidine Preparation Products And Raw materials |
|