- AMBRETTOLIDE
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- $2.00 / 1KG
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2019-12-20
- CAS:28645-51-4
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: ask
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| | AMBRETTOLIDE Basic information |
| Product Name: | AMBRETTOLIDE | | Synonyms: | AMBRETTOLIDE;OMEGA-6-HEXADECENLACTONE;Oxacycloheptadec-10-en-2-on;16-Hydroxy-9-hexadecenoic acid lactone;1-Oxacycloheptadeca-10-en-2-one;Δ9-Isooambrettolic acid lactone;9-Hexadecenoic acid, 16-hydroxy-, o-lactone;Einecs 249-120-7 | | CAS: | 28645-51-4 | | MF: | C16H28O2 | | MW: | 252.39 | | EINECS: | 249-120-7 | | Product Categories: | | | Mol File: | 28645-51-4.mol |  |
| | AMBRETTOLIDE Chemical Properties |
| Boiling point | 185-190 °C16 mm Hg(lit.) | | density | 0.956 g/mL at 25 °C(lit.) | | vapor pressure | 0.003Pa at 25℃ | | FEMA | 4145 | ISOAMBRETTOLIDE | | refractive index | n20/D 1.479(lit.) | | Fp | >230 °F | | storage temp. | Refrigerator | | solubility | Chloroform (Sparingly), Methanol (Sparingly) | | form | Oil | | color | Clear Colorless | | Odor | at 10.00 % in dipropylene glycol. sweet musk ambrette fruity waxy fatty | | Odor Type | musk | | Water Solubility | 15μg/L at 25℃ | | JECFA Number | 1991 | | LogP | 6.7 at 23℃ | | EPA Substance Registry System | Oxacycloheptadec-10-en-2-one (28645-51-4) |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 26-36 | | WGK Germany | 2 | | toxicity | Both the acute oral LD50 value in rats and the acute dermal LD50 value in rabbits exceeded 5 g/kg(Wohl, 1974). |
| | AMBRETTOLIDE Usage And Synthesis |
| Chemical Properties | AMBRETTOLIDE is not reported as being found in nature, in contrast
to (Z)-7-hexadecen-16-olide, which occurs in ambrette seed oil
and which is also referred to as ambrettolide. It is a colorless to slightly yellow
liquid, d204 0.949–0.957, n20D 1.477–1.482, with an intense and powerful musk
odor. It is prepared by treating aleuritic acid (9,10,16-trihydroxyhexadecanoic
acid) with trimethyl orthoformate to give a dioxolane derivative. Reaction with
acetic anhydride yields ??-acetoxy (E)-9-hexadecenoic acid methyl ester. This is
lactonized with potassium hydroxide to give the title compound . | | Occurrence | Found in oil of ambrette seed[Givaudan Index, 1961). | | Uses | Ambrettolide is a macrocyclic lactone that naturally occurs in ambrette seed oil. Ambrettolide is nontoxic, has a musky odour, and is commonly used as a fixative in perfume formulations. | | Preparation | From bromohexadecenoic acid(Bedoukian, 1967). | | Definition | ChEBI: Isoambrettolide is a macrolide. | | Flammability and Explosibility | Not classified |
| | AMBRETTOLIDE Preparation Products And Raw materials |
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