POLY-L-ARGININE HYDROCHLORIDE manufacturers
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| POLY-L-ARGININE HYDROCHLORIDE Basic information |
| POLY-L-ARGININE HYDROCHLORIDE Chemical Properties |
| POLY-L-ARGININE HYDROCHLORIDE Usage And Synthesis |
Uses | Poly-L-arginine hydrochloride has been used:
- to generate complex with stimulatory RNA isRNA9.2 as in neutrophils
- used in ribosomal RNA transfection into human monocytic THP-1 cells
- for coating alginate capsule beads
| Uses | Poly-L-arginine hydrochloride has been used:
- as polyelectrolyte solution in the synthesis of biodegradable capsules
- as layer constituent, in the preparation of layer by layer (LbL) assembly of multilayer biodegradable shells
- in assay for the determination of binding activity of C-reactive protein for polycationic ligands
| General Description | Poly-L-arginine hydrochloride (PLA) is a homopolyamino acid. PLA enhances membrane permeability compared to poly-L-lysine. It has applications as drug carrier, neuroprotective agent and in anticancer vaccines preparations. Peptide vaccines in conjugation with PLA promotes antigen-presenting cells (APCs) to generate T cell and elicit immunostimulant functionality. | Biochem/physiol Actions | Poly-L-arginine (PLA) possesses anti-bacterial activity. It has a greater capacity to enhance membrane permeability. PLA at lower concentration enhances cell proliferation and at higher concentration acts as antiproliferative agent. |
| POLY-L-ARGININE HYDROCHLORIDE Preparation Products And Raw materials |
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Tag:POLY-L-ARGININE HYDROCHLORIDE(26982-20-7)
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