| Company Name: |
LGM Pharma
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| Tel: |
1-(800)-881-8210 |
| Email: |
inquiries@lgmpharma.com |
| Products Intro: |
Product Name:DexverapaMil
CAS:38321-02-7
Purity:Typically NLT 98%
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| Company Name: |
Clearsynth Labs Limited
|
| Tel: |
+91-22-26355700 |
| Email: |
info@clearsynth.com |
| Products Intro: |
Product Name:R(+)-VERAPAMIL
CAS:38321-02-7
Remarks:CS-AC-39466
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
| Products Intro: |
Product Name:(R)-(+)-VerapamilHydrochloride
CAS:38321-02-7
Purity:NULL Package:1mg;2.5mg Remarks:NULL
|
| Company Name: |
QUALITY CONTROL SOLUTIONS LTD.
|
| Tel: |
13670046396 |
| Email: |
ORDERS@QCSRM.COM |
| Products Intro: |
Product Name:Verapamil Impurity 33
CAS:38321-02-7
Purity:95% HPLC Package:10MG;25MG;50MG;100MG
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| | (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Basic information |
| Product Name: | (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile | | Synonyms: | Dexverapamil;(aR)-a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile;Dexverapami;Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, (aR)- (9CI);Benzeneacetonitrile, a-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-, (R)-;d-Verapamil;(aR)-a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile Hydrochloride;Dexverapamil Hydrochloride | | CAS: | 38321-02-7 | | MF: | C27H38N2O4 | | MW: | 454.61 | | EINECS: | 253-878-4 | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 38321-02-7.mol | ![(+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Structure](CAS/GIF/38321-02-7.gif) |
| | (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Chemical Properties |
| Melting point | 129-131°C | | Boiling point | 586.1±50.0 °C(Predicted) | | density | 1.058±0.06 g/cm3(Predicted) | | pka | 8.97±0.50(Predicted) |
| | (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Uses | Both isomers inhibit the p-glycoprotein efflux pump in multidrug resistant tumor cells | | Definition | ChEBI: A 2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile that has R configuration. It competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1, EC 3.6.3.44), thereby p
tentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. Dexverapamil exhibits lower calcium antagonistic activity and toxicity than racemic verapamil. |
| | (+)-3-(3,4-dimethoxyphenyl)-6-[(5,6-dimethoxyphenethyl)methylamino]hexane-3-carbonitrile Preparation Products And Raw materials |
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