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| | Ascorbyl Tetraisopalmitate Basic information |
| Product Name: | Ascorbyl Tetraisopalmitate | | Synonyms: | ASCORBYL TETRA-2-HEXYLDECANOATE;L-Ascorbic acid, tetrakis(2-hexyldecanoate);L-Ascorbic acid,2,3,5,6-tetrakis(2-hexyldecanoate);Nikkol VC-IP;Vitamin C tetra-isopalmitate;[(2S)-2-[(2R)-3,4-bis(2-hexyldecanoyloxy)-5-oxo-2H-furan-2-yl]-2-(2-hexyldecanoyloxy)ethyl] 2-hexyldecanoate;NanoLiposomal Tetrahexyldecyl ascorbate ,NanoLiposomal VC-IP;Soluble VC-IP | | CAS: | 183476-82-6 | | MF: | C70H128O10 | | MW: | 1129.76 | | EINECS: | 430-110-8 | | Product Categories: | 183476-82-6 | | Mol File: | 183476-82-6.mol |  |
| | Ascorbyl Tetraisopalmitate Chemical Properties |
| alpha | [α]D20-25～-30° | | Boiling point | 947.4±64.0 °C(Predicted) | | density | 0.928～0.941g/mL (20℃) | | vapor pressure | 0Pa at 20℃ | | solubility | DMF: 2 mg/ml; DMSO: insol; Ethanol: 10 mg/ml; PBS (pH 7.2): insol | | form | A neat liquid | | InChIKey | OEWBEINAQKIQLZ-CMRBMDBWSA-N | | SMILES | C1(OC(=O)C(CCCCCC)CCCCCCCC)=C(OC(=O)C(CCCCCC)CCCCCCCC)C(=O)O[C@@H]1[C@@H](OC(=O)C(CCCCCC)CCCCCCCC)COC(=O)C(CCCCCC)CCCCCCCC | | LogP | 6.2 at 24℃ |
| | Ascorbyl Tetraisopalmitate Usage And Synthesis |
| Description | Ascorbyl Tetraisopalmitate, or ascorbyl tetra-2-hexyldecanoate, is a newly developed esterified derivative from Vitamin C with the highest stability among all Vitamin C derivatives. It can be absorbed transdermally and transferred into Vitamin C effectively; it can inhibit the synthesis of Melanin and remove the existing Melanin; accordingly, it activates collagen tissue directly at the skin base, accelerates collagen production and prevents skin ageing. In addition, it plays the role of an anti-inflammatory agent and antioxidant. It is suitable for all types of skincare, especially where whitening, brightening, detoxifying and purification properties are required. It is also effective at reducing redness and skin irritation. Ascorbyl tetraisopalmitate is oil soluble and ideal for anhydrous and emulsions products such as creams, lotions and milks - but can also be incorporated into water-based gels, sprays, serums and solutions.
| | Chemical Properties | 1. Excellent transdermal absorption;
2. Inhibit intracellular tyrosinase activity and melanin production;
3. Reduce cell/DNA damage caused by UV (anti-UV/anti-stress);
4. Prevent lipid peroxidation and skin aging (anti-oxidation);
5. Good solubility in common cosmetic oils;
6. SOD-like activity (antioxidant);
7. Collagen synthesis and collagen protection (anti-aging);
8. Stable to heat and oxidation. | | Physical properties | An oil-soluble vitamin C derivative with antioxidant, melanin inhibition and whitening properties. Similar to VC, it is easily absorbed by the skin, and the absorption rate is 16.5 times that of water-soluble vitamin C. | | Uses | Ascorbyl tetraisopalmitate (CAS# 183476-82-6) is a derivative of L-ascorbic acid (A786990) and is found in topicals and cosmetics as a skin hydrating component. Its inclusion in cosmetics is due to its increased stability compared to its parent form. | | Chemical Reactivity | Ascorbyl Tetraisopalmitate play a role in cosmetic, including skin lightening, promotion of collagen synthesis, and inhibition of lipid peroxidation. As a derivative of vitamin C, it is stable at high temperatures and has excellent skin absorption. Ascorbyl Tetraisopalmitate can be decomposed into free vitamin C in the skin to achieve physiological functions. |
| | Ascorbyl Tetraisopalmitate Preparation Products And Raw materials |
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