- friedelin
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- $0.00 / 1kg
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2024-10-25
- CAS:559-74-0
- Min. Order: 1kg
- Purity: 0.99
- Supply Ability: 20tons
- Friedelin
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- $48.00 / 1mg
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2024-10-24
- CAS:559-74-0
- Min. Order:
- Purity: ≥95%
- Supply Ability: 10g
- Friedelin
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- $0.00 / 5mg
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2023-02-24
- CAS:559-74-0
- Min. Order: 5mg
- Purity: ≥95%(HPLC)
- Supply Ability: 10 g
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| FRIEDELIN Basic information |
Product Name: | FRIEDELIN | Synonyms: | FRIEDELIN;DA-FRIEDOOLEANAN-3-ONE;FRIEDELIN, TECH.;FRIEDELIN hplc;FRIEDELIN WITH HPLC;DA-friedooleanan-3-one, Friedelan-3-one;D:A-Friedooleanan-3-one (van) (8ci)(9ci);Einecs 209-205-1 | CAS: | 559-74-0 | MF: | C30H50O | MW: | 426.72 | EINECS: | 209-205-1 | Product Categories: | Tri-Terpenoids | Mol File: | 559-74-0.mol | |
| FRIEDELIN Chemical Properties |
Melting point | 262-265 °C (lit.) | alpha | D -27.8° (chloroform) | Boiling point | 477.2±13.0 °C(Predicted) | density | 0.963±0.06 g/cm3(Predicted) | storage temp. | 2-8°C | solubility | Chloroform (Slightly), Methanol (Slightly) | form | Solid | color | White to Off-White | optical activity | -2214 (c 0.8, CHCl3) | Merck | 13,4293 | BRN | 1916451 | LogP | 10.287 (est) |
| FRIEDELIN Usage And Synthesis |
Uses | Friedelin is a flavonoid extract which displays radical scavenging and anti-typhoid activity. | Uses | Friedelin can be used as a starting material in the synthesis of:
- Friedel-3-enol acetate, friedel-2-oxo-3-enol acetate, friedel-2-ene derivatives and friedelin ketoxime.
- Oxygenated friedelin derivatives as potent DNA topoisomerase IIα inhibitors.
- Its 1,4-pyrazine derivatives as potent antimicrobial agents.
| Definition | ChEBI: Friedelin is a pentacyclic triterpenoid that is perhydropicene which is substituted by an oxo group at position 3 and by methyl groups at the 4, 4a, 6b, 8a, 11, 11, 12b, and 14a-positions (the 4R,4aS,6aS,6bR,8aR,12aR,12bS,14aS,14bS-enantiomer). It is the major triterpenoid constituent of cork. It has a role as an anti-inflammatory drug, a non-narcotic analgesic, an antipyretic and a plant metabolite. It is a pentacyclic triterpenoid and a cyclic terpene ketone. | General Description | Friedelin, a pentacyclic triterpene, is found in several plants like Cissus quadrangularis, Celastrus vulcanicola, Terminalia?avicennioides, and Alangium salvifolium. It is known to act as a histamine H1 receptor?(H1R) antagonist, anti-microbial, anti-HIV, and anti-cancer agent. |
| FRIEDELIN Preparation Products And Raw materials |
Raw materials | 6β,27-Dihydroxy-D:A-friedooleanan-3-one-->6β-Hydroxy-D:A-friedooleanan-3-one-->Kokoonol-->21-hydroxyfriedelan-3-one-->24,25,26-Trinoroleanan-3-one, 5,9,13-trimethyl-, (4α,5β,8α,9β,10α,13α,14β)--->3,4-Seco-3,4-epoxyfriedelane-3-one | Preparation Products | D:A-Friedoolean-3-ene |
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