| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:L-152,804;5,5-DiMethyl-2-(2,3,4,9-tetrahydro-3,3-diMethyl-1oxo-1H-xanthen-9-yl)-1,3-cyclohexanedione
CAS:6508-43-6
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| Company Name: |
EMMX Biotechnology LLC
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| Tel: |
888-539-0666 |
| Email: |
info@emmx.com |
| Products Intro: |
Product Name:L-152804
CAS:6508-43-6
Purity:98% HPLC Package:5mg;10mg;25mg;50mg;100mg;250mg;500mg;1g
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| | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE Basic information |
| Product Name: | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE | | Synonyms: | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE;L-152,804;5,5-Mmethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1-oxo-1H-xanthen-9-yl)-1,3 cyclohexanedione;9-(4,4-Dimethyl-2,6-dioxocyclohexyl)-1,2,3,4-tetrahydro-3,3-dimethyl-1-xanthenone;1,3-Cyclohexanedione, 5,5-dimethyl-2-(2,3,4,9-tetrahydro-3,3-dimethyl-1-oxo-1H-xanthen-9-yl)-;2-(3,3-Dimethyl-1-oxo-2,3,4,9-tetrahydro-1H-xanthen-9-yl)-5,5-dimethylcyclohexane-1,3-dione | | CAS: | 6508-43-6 | | MF: | C23H26O4 | | MW: | 366.45 | | EINECS: | | | Product Categories: | Neuropeptide Y (NPY ) receptor | | Mol File: | 6508-43-6.mol |  |
| | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE Chemical Properties |
| Melting point | 207-208 °C | | Boiling point | 513.7±50.0 °C(Predicted) | | density | 1.20±0.1 g/cm3(Predicted) | | storage temp. | Desiccate at +4°C | | solubility | DMSO: soluble5mg/mL, clear (warmed) | | form | powder | | pka | 4.86±0.42(Predicted) | | color | white to beige |
| Hazard Codes | T,N | | Risk Statements | 25-50/53 | | Safety Statements | 45-60-61 | | RIDADR | UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all | | WGK Germany | 3 |
| | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE Usage And Synthesis |
| Uses | L-152,804 is a potent and orally available Y5 antagonist, which is the receptor postulated to be responsible for hypothalamic "feeding". | | Definition | ChEBI: 2-(3,3-dimethyl-1-oxo-4,9-dihydro-2H-xanthen-9-yl)-5,5-dimethylcyclohexane-1,3-dione is a member of xanthenes. | | Biological Activity | Potent, selective non-peptide neuropeptide Y Y 5 receptor antagonist (K i = 26 nM for hY 5 ). Displays > 300-fold selectivity over hY 1 , hY 2 , and hY 4 receptors. Causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure. Centrally active upon oral administration in vivo . | | storage | Desiccate at +4°C |
| | 5,5-DIMETHYL-2-(2,3,4,9-TETRAHYDRO-3,3-DIMETHYL-1OXO-1H-XANTHEN-9-YL)-1,3-CYCLOHEXANEDIONE Preparation Products And Raw materials |
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