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| | SULINDAC SULFIDE Basic information |
| Product Name: | SULINDAC SULFIDE | | Synonyms: | (Z)-5-fluoro-2-methyl-1-[[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid;(Z)-5-FLUORO-2-METHYL-1-(4-METHYLTHIOBENZYLIDENE)-1H-INDEN-3-YLACETIC ACID;5-Fluoro-2-methyl-1-[(Z)-[4-(methylthio)phenyl]methylene]-1H-indene-3-acetic acid;(Z)-Sulindac sulfide;1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylthio)phenyl)methylene)-, (Z)-;Einecs 256-403-9;SULINDAC SULPHIDE;(Z)-5-FLUORO-2-METHYL-1-[P-(METHYLTHIO)BENZYLIDENE]INDENE-3-ACETIC ACID | | CAS: | 49627-27-2 | | MF: | C20H17FO2S | | MW: | 340.41 | | EINECS: | 256-403-9 | | Product Categories: | Intermediates & Fine Chemicals;Metabolites;Pharmaceuticals | | Mol File: | 49627-27-2.mol |  |
| | SULINDAC SULFIDE Chemical Properties |
| Melting point | 189-191°C | | storage temp. | -20°C Freezer | | solubility | DMSO: >22 mg/mL | | form | solid | | color | yellow |
| Hazard Codes | Xn | | Risk Statements | 22-42/43-63 | | WGK Germany | 3 | | HS Code | 2930902000 |
| | SULINDAC SULFIDE Usage And Synthesis |
| Chemical Properties | Yellow Solid | | Uses | An active metabolite of Sulindac. Inhibits cyclooxygenase, but induces apoptosis by a cyclooxygenase-independent mechanism. Inhibition of Ras activation of Ref-1. Impairs nucleotide exchange on Ras by CDC25 and accelerates Ras hydrolysis of GTP by p120GAP. | | Definition | ChEBI: An aryl sulfide that is a metabolite of sulindac. A non-steroidal anti-inflammatory drug, which also has anticancer activity. |
| | SULINDAC SULFIDE Preparation Products And Raw materials |
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