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Postion:Product Catalog >Pharmaceutical intermediates>Bulk Drug Intermediates> 3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine
	3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine
  • 	3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine
  • 	3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine

3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine NEW

Price $10 $5 $3
Package 1kg 25kg 180kg
Min. Order: 1kg
Supply Ability: g-kg-tons, free sample is available
Update Time: 2024-04-29

Product Details

Product Name: 3-(4-Phenoxyphenyl)-1h-pyrazolo[3,4-d]pyrimidin-4-amine CAS No.: 330786-24-8
Min. Order: 1kg Purity: 99%
Supply Ability: g-kg-tons, free sample is available Release date: 2024/04/29
Lead time: In stock Origin: Manufacturer
Packaging: bottle/drum/bucket/IBC, as request. Delivery: By sea, by air, by express
Name: Sun

1. Product information

Names

Name3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
SynonymMore Synonyms

 Ibrutinib deacryloylpiperidine Biological Activity

DescriptionIbrutinib deacryloylpiperidine (IBT4A) is an impurity of Ibrutinib[1]. Ibrutinib is a selective, irreversible Btk inhibitor with an IC50 of 0.5 nM[2].
Related Catalog
Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk
References

[1]. Somana Siva Prasad, et al. A QUALITY BY DESIGN APPROACH FOR DEVELOPMENT OF SIMPLE AND ROBUST REVERSED PHASE STABILITY INDICATING HPLC METHOD FOR ESTIMATION OF IBRUTINIB AND ITS IMPURITIES.

[2]. Honigberg LA, et al. The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13075-80.

 Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point577.4±50.0 °C at 760 mmHg
Molecular FormulaC17H13N5O
Molecular Weight303.318
Flash Point303.0±30.1 °C
Exact Mass303.112000
PSA89.71000
LogP3.01
Vapour Pressure0.0±1.6 mmHg at 25°C
Index of Refraction1.734
Storage condition2-8°C

 Safety Information

Hazard CodesXi

 Precursor & DownStream

Precursor  2



  • Article illustration CAS#:2215-77-2
    4-Phenoxybenzoi...

  • Article illustration CAS#:330792-69-3
    Propanedinitril...

DownStream  0



 Synonyms

3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 3-(4-phenoxyphenyl)-
3-(4-Phenoxyphenyl)-1H-pyrazolo(3,4d)pyrimidin-4-amine
5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMine
Ibrutinib Impurity 8

2. Packaging

For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                     Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address : sun@fdachem.com

Mob: 86 13526505137

WhatsApp/Skype/Wechat/: 86 13526505137





Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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  • Since: 2023-02-10
  • Address: Room 01, 2288 E05, Building 14, East Henan University, Science and Technology Park, 279 Xisanhuan Ro
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