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Postion:Product Catalog >Chemical Reagents>Organic reagents>Aromatic acids>3,4-Dihydroxyphenylacetic acid
3,4-Dihydroxyphenylacetic acid
  • 3,4-Dihydroxyphenylacetic acid
  • 3,4-Dihydroxyphenylacetic acid
  • 3,4-Dihydroxyphenylacetic acid
  • 3,4-Dihydroxyphenylacetic acid
  • 3,4-Dihydroxyphenylacetic acid

3,4-Dihydroxyphenylacetic acid NEW

Price Get Latest Price
Package 25KG
Min. Order: 1KG
Supply Ability: 50000KG/month
Update Time: 2023-11-16

Product Details

Product Name: 3,4-Dihydroxyphenylacetic acid CAS No.: 102-32-9
EC-No.: 203-024-1 Min. Order: 1KG
Purity: 99% Supply Ability: 50000KG/month
Release date: 2023/11/16

CAS:102-32-9
MF:C8H8O4
MW:168.15
EINECS:203-024-1
Product Categories:buildingblock;Aromatic Phenylacetic Acids and Derivatives
Mol File:102-32-9.mol
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3,4-Dihydroxyphenylacetic acid Chemical Properties
Melting point 127-130 °C (lit.)
Boiling point 257.07°C (rough estimate)
density 1.3037 (rough estimate)
refractive index 1.5090 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility water: soluble50mg/mL, clear, almost colorless
pka4.42±0.10(Predicted)
form Powder, Crystals or Lumps
color White to off-white
Water Solubility Soluble in water and methanol.
BRN 2211017
InChIInChI=1S/C8H8O4/c9-6-2-1-5(3-7(6)10)4-8(11)12/h1-3,9-10H,4H2,(H,11,12)
InChIKeyCFFZDZCDUFSOFZ-UHFFFAOYSA-N
SMILESC1(CC(O)=O)=CC=C(O)C(O)=C1
LogP0.980
CAS DataBase Reference102-32-9(CAS DataBase Reference)
NIST Chemistry ReferenceAcetic acid, (3,4-dihydroxyphenyl)-,(102-32-9)
EPA Substance Registry System3,4-Dihydroxyphenylacetic acid (102-32-9)
3,4-Dihydroxyphenylacetic acid Usage And Synthesis
Description3,4-Dihydroxyphenylacetic acid (DOPAC) is a metabolite of the neurotransmitter dopamine. Dopamine can be metabolized into one of three substances. One such substance is DOPAC. Another is 3-methoxytyramine (3-MT). Both of these substances are degraded to form homovanillic acid (HVA). Both degradations involve the enzymes monoamine oxidase (MAO) and catechol-O-methyl transferase (COMT), albeit in reverse order: MAO catalyzes dopamine to DOPAC, and COMT catalyzes DOPAC to HVA; whereas COMT catalyzes dopamine to 3-MT and MAO catalyzes 3-MT to HVA. The third metabolic end-product of dopamine is norepinephrine (noradrenaline).
DOPAC can be oxidized by hydrogen peroxide, leading to the formation of toxic metabolites which destroy dopamine storage vesicles in the substantia nigra. This may contribute to the failure of levodopa treatment of Parkinson's disease. A MAO-B inhibitor such as selegiline or rasagiline can prevent this from happening.
wikipedia
Chemical Propertiesbeige to light brown crystalline powder
Uses3,4-Dihydroxyphenylacetic Acid is a metabolite of Dopamine (D533782).
Uses3,4-Dihydroxyphenylacetic acid is an important metabolite when studying the behavior of the dopaminergic system.
DefinitionChEBI: (3,4-dihydroxyphenyl)acetic acid is a dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine. It has a role as a human metabolite. It is a dihydroxyphenylacetic acid and a member of catechols. It is functionally related to a phenylacetic acid. It is a conjugate acid of a (3,4-dihydroxyphenyl)acetate.
General Description3,4-dihydroxyphenylacetic acid (DOPAC) is a normal constituent of rat brain tissue. A mass fragmentographic method for determination of DOPAC in rat brain tissue has been described. It is major metabolite of dopamine (DA). The voltammetric reduction of DOPAC has been studied at a glassy carbon electrode modified with single-wall carbon nanotubes (SWNTs). Semi-automatic fluorometric assay technique for DOPAC has been reported.

Packing &shipping&Payment

Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
Quantity(Kilograms)1 - 10000>10000
Est. Time(days)5To be negotiated

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Article illustrationCompany information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.

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