antibioticbc757 NEW
| Price | Get Latest Price |
| Package | 25KG |
| Min. Order: | 1KG |
| Supply Ability: | 50000KG/month |
| Update Time: | 2023-08-30 |
Product Details
| Product Name: antibioticbc757 | CAS No.: 125-65-5 |
| EC-No.: 204-747-5 | Min. Order: 1KG |
| Purity: 99% | Supply Ability: 50000KG/month |
| Release date: 2023/08/30 |
| CAS: | 125-65-5 |
| MF: | C22H34O5 |
| MW: | 378.5 |
| EINECS: | 204-747-5 |
| Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals |
| Mol File: | 125-65-5.mol |
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| Pleuromulin Chemical Properties |
| Melting point | 170-1710C |
| alpha | D24 +20° (c = 3 in abs ethanol) |
| Boiling point | 482.8±45.0 °C(Predicted) |
| density | 1.15±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO: >10mg/mL (warmed) |
| pka | 12.91±0.10(Predicted) |
| form | powder |
| color | white to beige |
| optical activity | [α]/D +30 to +40° (c=1; CH2Cl2) |
| InChIKey | YSBXUHAJXRCCET-BKUNHTPHSA-N |
| Pleuromulin Usage And Synthesis |
| Description | Pleuromutilin is an antibiotic derived from the fungus Clitopilus that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase component of the 50S subunit and inhibiting peptide bond formation. |
| Chemical Properties | Pleuromulin is Crystalline Solid |
| Uses | Pleuromutilin is a diterpene produced by several species of basidomycete, notably the genus Pleurotus, discovered in 1951. Pleuromutilin is a potent and highly selective antibiotic active against a range of Gram positive bacteria, with no cross resistance to existing antibiotic classes due to its unique mode of action. Pleuromutilin inhibits protein synthesis by binding to domain V of 23S rRNA and this has led to the development of many semi-synthetic analogues as new generation antibiotics, such as tiamulin and retapamulin. Pleuromutilins such as tiamulin and valnemulin have been used for some time in veterinary medicine to treat swine infections. More recently a semisynthetic pleuromutilin, retapamulin, has been introduced as a topical treatment for Gram-positive infections in humans. Pleuromutilins inhibit the peptidyl transferase activity of the bacterial 50S ribosomal subunit by binding to the A site. |
| Uses | Antibiotic substance produced by the basidiomycetes Pleurotus mutilus. |
| references | [1]. kilaru s, collins cm, hartley aj, et al. establishing molecular tools for genetic manipulation of the pleuromutilin-producing fungus clitopilus passeckerianus. appl environ microbiol. 2009 nov;75(22):7196-204. [2]. long ks, hansen lh, jakobsen l, et al. interaction of pleuromutilin derivatives with the ribosomal peptidyl transferase center. antimicrob agents chemother. 2006 apr;50(4):1458-62. |
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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China- Since: 2017-12-08
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