TRIETHYLENE GLYCOL MONOBUTYL ETHER
Product identifier
- Product name: TRIETHYLENE GLYCOL MONOBUTYL ETHER
- CBnumber: CB0453855
- CAS: 143-22-6
- EINECS Number: 205-592-6
- Synonyms: Triethylene glycol monobutyl ether,BUTOXYTRIGLYCOL
Relevant identified uses of the substance or mixture and uses advised against
- Relevant identified uses: For R&D use only. Not for medicinal, household or other use.
- Uses advised against: none
Company Identification
- Company: Chemicalbook
- Address: Building 1, Huihuang International, Shangdi 10th Street, Haidian District, Beijing
- Telephone: 400-158-6606
Classification of the substance or mixture
Serious eye damage, Category 1
Label elements
Pictogram(s)
- Signal wordDanger
H318 Causes serious eye damage
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...
P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P317 Get medical help.
none
none
Other hazards
no data available
Substance
- Product name: TRIETHYLENE GLYCOL MONOBUTYL ETHER
- Synonyms: Triethylene glycol monobutyl ether,BUTOXYTRIGLYCOL
- CAS: 143-22-6
- EC number: 205-592-6
- MF: C10H22O4
- MW: 206.28
Description of first aid measures
If inhaledFresh air, rest.
Rinse skin with plenty of water or shower.
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
Rinse mouth.
Most important symptoms and effects, both acute and delayed
no data available
Indication of any immediate medical attention and special treatment needed
Absorption, Distribution and ExcretionHuman abdominal whole skin (2.54 cm sq) was mounted in a glass diffusion apparatus (at 30 +/- 1 degree C) and the diffusion of triethylene glycol monobutyl ether was monitored during a 12-hr period using gas chromatography (n=6). The integrity of the epidermal membranes was first assessed by measuring permeability of membranes to tritiated water. Epidermal membranes displaying permeability constants greater than 1.5 x 10E-3 cm/hr were deemed to have been damaged during preparation and were rejected. The mean steady state of absorption for triethylene glycol monobutyl ether was 22.2 ug/cm sq/hr (SD +/- 8.59), which was 100-fold less than that of ethylene glycol monomethyl ether. Test material did not increase permeability of the membrane (damage ratio of 1.26).
Extinguishing media
Use water spray, powder, alcohol-resistant foam, carbon dioxide.
Specific Hazards Arising from the Chemical
Combustible.
Advice for firefighters
Use water spray, powder, alcohol-resistant foam, carbon dioxide.
NFPA 704
| HEALTH | 0 | Poses no health hazard, no precautions necessary and would offer no hazard beyond that of ordinary combustible materials | |
| FIRE | 1 | Materials that require considerable preheating, under all ambient temperature conditions, before ignition and combustion can occur. Includes some finely divided suspended solids that do not require heating before ignition can occur. Flash point at or above 93.3 °C (200 °F). (e.g. mineral oil, ammonia) | |
| REACT | 0 | Normally stable, even under fire exposure conditions, and is not reactive with water (e.g. helium,N2) | |
| SPEC. HAZ. |
Personal precautions, protective equipment and emergency procedures
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water.
Environmental precautions
Personal protection: filter respirator for organic gases and vapours adapted to the airborne concentration of the substance. Ventilation. Collect leaking and spilled liquid in sealable containers as far as possible. Wash away remainder with plenty of water.
Methods and materials for containment and cleaning up
Collect and arrange disposal. Keep the chemical in suitable and closed containers for disposal. Remove all sources of ignition. Use spark-proof tools and explosion-proof equipment. Adhered or collected material should be promptly disposed of, in accordance with appropriate laws and regulations.
Precautions for safe handling
NO open flames. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
Control parameters
Occupational Exposure limit valuesno data available
no data available
Exposure controls
Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.
Individual protection measures
Eye/face protectionWear safety goggles.
Protective gloves.
Use ventilation.
no data available
Information on basic physicochemical properties
- Physical state
Liquid.
- Colour
Colourless.
- Odour
Mild smelling
- Melting point/freezing point
-35.2 °C. Atm. press.:1 atm.
- Boiling point or initial boiling point and boiling range
278 °C. Atm. press.:1 atm.
- Flammability
Combustible.
- Lower and upper explosion limit/flammability limit
no data available
- Flash point
131 °C. Atm. press.:1 013.25 hPa.
- Auto-ignition temperature
202 °C. Atm. press.:1 013.25 hPa.
- Decomposition temperature
no data available
- pH
7. Remarks:7; neutral.
- Kinematic viscosity
kinematic viscosity (in mm2/s) = 9.2. Temperature:25.0°C. Remarks:Equivalent to a dynamic viscosity of 9.1 mPas.
- Solubility
Very soluble in ethanol, methanol
- Partition coefficient n-octanol/water
log Pow = 0.51. Temperature:25 °C.
- Vapour pressure
0.003 mm Hg. Temperature:25 °C. Remarks:Experimentally derived value.;0.001 mm Hg. Temperature:25 °C. Remarks:Value from a QSAR.
- Density and/or relative density
Ca. 989 kg/m3. Temperature:20 °C.
- Relative vapour density
no data available
- Particle characteristics
no data available
Reactivity
no data available
Chemical stability
no data available
Possibility of hazardous reactions
Combustible
Conditions to avoid
no data available
Incompatible materials
Glycol ethers, glycols, ketones, and alcohols undergo violent decomposition in contact with 68-72% perchloric acid
Hazardous decomposition products
When heated to decomposition it emits acrid smoke and irritating fumes.
Acute toxicity
- Oral: LD50 - rat (male/female) - 5 170 mg/kg bw.
- Inhalation: LCLo - rat (male/female) - 1 200 mg/m3 air.
- Dermal: LD50 - rabbit (male) - 3 540 mg/kg bw.
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
no data available
Reproductive toxicity
no data available
STOT-single exposure
The substance is irritating to the eyes. The substance is mildly irritating to the skin.
STOT-repeated exposure
The substance defats the skin, which may cause dryness or cracking.
Aspiration hazard
A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20°C.
Toxicity
- Toxicity to fish: LC50 - Leuciscus idus - 2 200 - 4 600 mg/L - 96 h.
- Toxicity to daphnia and other aquatic invertebrates: LC50 - Daphnia magna - 2 210 mg/L - 48 h.
- Toxicity to algae: EC10 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - 612.6 mg/L - 72 h.
- Toxicity to microorganisms: Toxicity threshold (TT) or EC3 or (~NOEC) - Pseudomonas putida - 1 221 mg/L - 16 h.
Persistence and degradability
AEROBIC: The theoretical BODs for triethylene glycol monobutyl ether are 0, 5, and 24% for 5 days, 10 days, and 20 days, respectively, indicating that it will be partially removed from biological wastewater treatment plants(1).
Bioaccumulative potential
An estimated BCF of 3 was calculated in fish for triethylene glycol monobutyl ether(SRC), using an estimated log Kow of 0.02(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).
Mobility in soil
Using a structure estimation method based on molecular connectivity indices(1), the Koc of triethylene glycol monobutyl ether can be estimated to be 10(SRC). According to a classification scheme(2), this estimated Koc value suggests that triethylene glycol monobutyl ether is expected to have very high mobility in soil(SRC).
Other adverse effects
no data available
Disposal methods
ProductThe material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
UN Number
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
UN Proper Shipping Name
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Transport hazard class(es)
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Packing group, if applicable
ADR/RID: Not dangerous goods. (For reference only, please check.)
IMDG: Not dangerous goods. (For reference only, please check.)
IATA: Not dangerous goods. (For reference only, please check.)
Environmental hazards
ADR/RID: No
IMDG: No
IATA: No
Special precautions for user
no data available
Transport in bulk according to IMO instruments
no data available
Safety, health and environmental regulations specific for the product in question
European Inventory of Existing Commercial Chemical Substances (EINECS)Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
The information in this MSDS is only applicable to the specified product, unless otherwise specified, it is not applicable to the mixture of this product and other substances. This MSDS only provides information on the safety of the product for those who have received the appropriate professional training for the user of the product. Users of this MSDS must make independent judgments on the applicability of this SDS. The authors of this MSDS will not be held responsible for any harm caused by the use of this MSDS.