ChemicalBook CAS DataBase List 2-CHLOROETHANESULFONYL CHLORIDE

2-CHLOROETHANESULFONYL CHLORIDE synthesis

10synthesis methods

Product Name:2-CHLOROETHANESULFONYL CHLORIDE
CAS Number:1622-32-8
Molecular formula:C2H4Cl2O2S
Molecular Weight:163.02

1562-00-1 Synthesis

1562-00-1
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1622-32-8
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Yield:1622-32-8 90%

Reaction Conditions:

with thionyl chloride in dichloromethane;N,N-dimethyl-formamide at 20 - 60;

Steps:

9.A
Example 9; Preparation of N-Methyl vinyl sulfonamide; PART A: A mixture of isethionic acid sodium salt (0.250 Kg, 1689 mmol) was taken inDMF (0.32L) and dichloromethae (0.3L). To this mixture thionyl chloride (0.375L, 5186mmol) was added dropwise at 20-30°C. The reaction mixture was heated slowly from 30-60 "C. After completion of the reaction 3.5 lit of chilled water was added. The reaction mixture was extracted with 3x0.5L dichloromethane. Then dichloromethane was distilled out from the reaction mixture to get an oil. [ Yield 0.250Kg, 90%] which was distilled under vacuum to get pure chloroethane sulfonyl chloride. (0.225kg, 90%).

References:

USV LIMITED WO2009/118753, 2009, A2 Location in patent:Page/Page column 28-29

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870-24-6 Synthesis