2-Iodobenzyl alcohol synthesis
- Product Name:2-Iodobenzyl alcohol
- CAS Number:5159-41-1
- Molecular formula:C7H7IO
- Molecular Weight:234.03
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Yield:-
Reaction Conditions:
with sodium tetrahydroborate;[fac-8-(2-diphenylphosphinoethyl)amidotrihydroquinoline]RuH(PPh3)(CO);hydrogen in tetrahydrofuran at 120; under 38002.6 Torr; for 12 h;Autoclave;Industrial scale;
Steps:
3-5 example 3-5
General procedure: (1 mmol) of NaBH44, 3.08 g (20 mmol, S: B: C: 2000: 20: 1) of methyl o-fluorobenzoate were sequentially added to 100 mL of a glass bottle in a ratio of 7.51 mg ),The reaction system was placed in a 100mL autoclave, replaced with hydrogen three times, rushed into hydrogen 50atm, temperature set at 120 , heating and stirring reaction 18 hours, the reactor was placed in an ice bath to room temperature, venting gas .GC analysis of the reaction solution specific results in Table III. In addition to o-iodobenzoate 5.24g (20mol, S: B: C = 2000: 20: 1), heated and stirred 12 hours, itshydrogenation reduction reaction performed with the same as in Example 3-1, the specific results in Table three.
References:
Hebei Normal University;Liu, Qingbin;Wang, Zheng;Liu, Bo;Zhang, Fujun CN105237342, 2016, A Location in patent:Paragraph 0023; 0027; 0040
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5159-41-1
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5159-41-1
214 suppliers
$8.00/5g