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ChemicalBook CAS DataBase List 2-PHENYLETHYL PROPIONATE

2-PHENYLETHYL PROPIONATE synthesis

9synthesis methods
By esterification of phenyl alcohol with propionic acid.
-

Yield:-

Steps:

Multi-step reaction with 3 steps
1: [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; isopropyl alcohol; potassium tert-butylate / 100 °C / Schlenk technique; Inert atmosphere
2: pyridine / dichloromethane / 0 - 20 °C
3: [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; cesium acetate; isopropyl alcohol / 100 °C / Schlenk technique; Inert atmosphere

References:

You, Tingjie;Wang, Zhenrong;Chen, Jiajia;Xia, Yuanzhi [Journal of Organic Chemistry,2017,vol. 82,# 3,p. 1340 - 1346]

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